LncRNAs are cool regulators in cold exposure in plants
LncRNAs are cool regulators in cold exposure in plants
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DOI：
10.1007/s11427-019-9575-3
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发表时间：
2019-06
期刊：
影响因子：
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通讯作者：
Pingchuan Deng;Liang Wu
中科院分区：
文献类型：
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作者：
Pingchuan Deng;Liang Wu
近二十年来的转录组学研究表明，70%以上的真核生物基因组是转录的。那些长度超过200个核苷酸而没有编码能力的转录物，称为长非编码RNA（lncRNA），占转录基因组的最大部分（Deng et al. 2018年）。在动物中，lncRNA长期以来被广泛认为是基因表达的关键调节剂。然而，除了IPS 1，其被证明是抑制miRNA活性的miRNA靶标模拟物（Franco-Zorrilla et al.，2007），直到最近十年，关于lncRNA的方式在植物中取得的进展的迹象有限。由于强大的遗传筛选方法，最近已经认识到一些lncRNA对作物的农艺性状起着至关重要的作用。例如，已发现两种基因间lncRNA PMS 1 T和LDMAR可调节水稻光周期敏感雄性不育（Fan和Zhang，2018），而LAIR（反义转录本）
Transcriptomic studies in last two decades showed that more than 70% eukaryotic genomes are transcribed. Those transcripts over 200 nucleotides in length without a coding ability, called long non-coding RNAs (lncRNAs), account for the largest portion of transcribed genomes (Deng et al., 2018). In animals, lncRNAs have been extensively recognized as critical modulators of gene expressions for a long time. However, except IPS1, which was demonstrated as a miRNA target mimicry to inhibit miRNA activity (Franco-Zorrilla et al., 2007), limited signs of progress were made in plants regarding the manners of lncRNAs until the last decade.Thanks to the powerful genetic screening approaches, a couple of lncRNAs have been recently recognized as crucial contributors to agrarian traits in crops. For instance, two intergenic lncRNAs, PMS1T and LDMAR, have been revealed to regulate rice photoperiod-sensitive male sterility (Fan and Zhang, 2018), while LAIR, the antisense transcript