Do large dogs die young?
Do large dogs die young?
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DOI：
10.1002/jez.b.21116
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发表时间：
2007-03-15
影响因子：
2.2
通讯作者：
Nussbaumer, Marc
中科院分区：
文献类型：
--
作者：
Galis, Frietson;Van Der Sluijs, Inke;Nussbaumer, Marc
在大多数动物类群中，寿命随着物种的体型而增加，正如衰老的氧化应激理论所预测的那样。相比之下，在哺乳动物特别是家犬的种内比较中（例如Patronek等人，'97; Michell，'99; Egenvall等人，2000; Speakman等人，2003），寿命随着身体大小而减少。我们探索了两个狗的数据集，如果我们考虑到品种之间的差异，我们发现大小和寿命之间存在负相关关系。然而，在品种内，这种关系不是负的，在两个数据集中较大的数据集中，这种关系是轻微的，但显着的，积极的。负跨品种的关系可能是在大型品种寿命短的后果。人工选择在大型品种极高的增长率似乎已经导致了严重减少寿命的发育疾病。
In most animal taxa, longevity increases with body size across species, as predicted by the oxidative stress theory of aging. In contrast, in within-species comparisons of mammals and especially domestic dogs (e.g. Patronek et al., '97; Michell, '99; Egenvall et al., 2000; Speakman et al., 2003), longevity decreases with body size.We explore two datasets for dogs and find support for a negative relationship between size and longevity if we consider variation across breeds. Within breeds, however, the relationship is not negative and is slightly, but significantly, positive in the larger of the two datasets. The negative across-breed relationship is probably the consequence of short life spans in large breeds. Artificial selection for extremely high growth rates in large breeds appears to have led to developmental diseases that seriously diminish longevity.