Mapping the global distribution of podoconiosis: Applying an evidence consensus approach
Mapping the global distribution of podoconiosis: Applying an evidence consensus approach
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DOI：
10.1371/journal.pntd.0007925
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发表时间：
2019-12-01
影响因子：
3.8
通讯作者：
Davey, Gail
中科院分区：
文献类型：
--
作者：
Deribe, Kebede;Simpson, Hope;Davey, Gail
背景足尘病是一种以小腿肿胀为特征的象皮病。它经常与热带水肿的其他原因混淆，其全球分布不确定。在这里，我们综合了现有的信息，足尘病的存在，以产生证据共识地图，其全球地理distribution.Methods和findingsWe系统地搜索现有的数据，足尘病在SCOPUS和MEDLINE从一开始，更新到2019年5月10日，并确定观察和基于人群的研究报告足尘病。为了确定足尘病的存在，我们使用了研究中报告的病例数和地理位置的患病率数据。然后，我们开发了一个评估证据质量和可靠性的指数，为每个国家分配一个证据共识得分。使用这些总结分数，我们然后开发了一个当代全球地图的国家层面的足尘病状态。有证据表明，足尘病在17个国家（12个在非洲，3个在拉丁美洲，2个在亚洲）和共识的存在在6个国家（所有在非洲）。我们已经确定了需要进行监测以进一步确定是否存在足尘病的国家。我们已经强调了证据不足或相互矛盾的领域，并从中获得更多的证据是need.ConclusionThe全球分布的podoconiosis是不清楚的，疾病的范围和限制在这里提供的通知最好的当代地图的分布全球podoconiosis从现有的数据。这些结果有助于确定监测需求，指导未来的绘图活动，并为预防计划和足尘病的负担估计提供信息。
BackgroundPodoconiosis is a type of elephantiasis characterised by swelling of the lower legs. It is often confused with other causes of tropical lymphedema and its global distribution is uncertain. Here we synthesise the available information on the presence of podoconiosis to produce evidence consensus maps of its global geographical distribution.Methods and findingsWe systematically searched available data on podoconiosis in SCOPUS and MEDLINE from inception, updated to 10 May, 2019, and identified observational and population-based studies reporting podoconiosis. To establish existence of podoconiosis, we used the number of cases reported in studies and prevalence data with geographical locations. We then developed an index to assess evidence quality and reliability, assigning each country an evidence consensus score. Using these summary scores, we then developed a contemporary global map of national-level podoconiosis status.There is evidence of podoconiosis in 17 countries (12 in Africa, three in Latin America, and two in Asia) and consensus on presence in six countries (all in Africa). We have identified countries where surveillance is required to further define the presence or absence of podoconiosis. We have highlighted areas where evidence is currently insufficient or conflicting, and from which more evidence is needed.ConclusionThe global distribution of podoconiosis is not clearly known; the disease extent and limits provided here inform the best contemporary map of the distribution of podoconiosis globally from available data. These results help identify surveillance needs, direct future mapping activities, and inform prevention plans and burden estimation of podoconiosis.