Factors Influencing Maturation Time of Native Arteriovenous Fistulas
Factors Influencing Maturation Time of Native Arteriovenous Fistulas
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DOI：
10.1016/j.avsg.2014.11.026
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发表时间：
2015-05-01
影响因子：
1.5
通讯作者：
Woo, Karen
中科院分区：
文献类型：
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作者：
Dunn, Joie;Herscu, Gabriel;Woo, Karen
背景资料：为了确定影响自体动静脉内瘘成熟时间的因素，方法：对2004年至2009年来自一所大学相关透析中心的血液透析患者进行回顾性分析。记录人口统计学、合并症和保险状况。成熟时间被定义为从访问创建的时间，直到访问能够定期用于血液透析的一段时间为2 weeks.Results：共249例患者被确定在研究期间谁有一个动静脉瘘创建，成功成熟; 104（42%）例患者是女性和145（58%）是男性。大多数患者为西班牙裔（82%）。97名患者（39%）有医疗补助型保险，133名患者（53%）有医疗保险。平均年龄为51岁，190例（76%）患者患有糖尿病。总体平均成熟时间为79天。女性的瘘管成熟时间明显长于男性（91.9天vs. 70.5天，P = 0.0028）。糖尿病患者的成熟时间也明显长于非糖尿病患者（92.5天vs. 75.4天，P = 0.0004）。年龄对成熟时间没有影响。多变量分析，性别仍然显着（P = 0.007），但是，糖尿病失去了其significant.Conclusions：在这个主要是西班牙裔血液透析人群，女性需要更长的瘘成熟时间比男性。根据这些数据，其确切原因尚不清楚。需要更多的研究来确定这种性别差异的病因。
Background: To determine the factors influencing the maturation time of native arteriovenous fistulas.Methods: A retrospective review was performed of hemodialysis patients from a single university-associated dialysis center from 2004 to 2009. Demographics, comorbidities, and insurance status were recorded. Maturation time was defined as the time from access creation until the access was able to be used regularly for hemodialysis for a period of 2 weeks.Results: A total of 249 patients were identified during the study period who had an arteriovenous fistula created that successfully matured; 104 (42%) patients were women and 145 (58%) were men. Most of the patients were Hispanic (82%). Ninety-seven (39%) of the patients had Medicaid-type insurance and 133 (53%) had Medicare. The mean age was 51 years, and 190 (76%) of the patients had diabetes. The overall mean maturation time was 79 days. Women had a significantly longer time to fistula maturation than males (91.9 days vs. 70.5 days, P = 0.0028). Diabetics also had a significantly longer maturation time than nondiabetics (92.5 days vs. 75.4 days, P = 0.0004). Age did not have an effect on maturation time. On multivariable analysis, sex remained significant (P = 0.007), however, diabetes lost its significance.Conclusions: In this predominantly Hispanic hemodialysis population, women require longer fistula maturation times than men. The exact reasons for this are unknown based on this data. More study is required to determine the etiology of this gender discrepancy.