Functional organization of spatial and nonspatial working memory processing within the human lateral frontal cortex
Functional organization of spatial and nonspatial working memory processing within the human lateral frontal cortex
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DOI：
10.1073/pnas.95.13.7721
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发表时间：
1998-06-23
影响因子：
11.1
通讯作者：
Petrides, M
中科院分区：
文献类型：
--
作者：
Owen, AM;Stern, CE;Petrides, M
本研究使用功能磁共振成像技术证明，当所有与刺激材料类型无关的因素都被适当控制时，视觉空间和视觉非空间工作记忆任务涉及到外侧前额叶皮质的相同区域。这些结果证明，空间和非空间工作记忆可能不像人们普遍认为的那样，分别由额叶中背外侧区和中腹外侧区介导，并支持另一种观点，即额叶外侧前额叶特定区域对空间和非空间工作记忆的执行功能贡献相同。
The present study used functional magnetic resonance imaging to demonstrate that performance of visual spatial and visual nonspatial working memory tasks involve the same regions of the lateral prefrontal cortex when all factors unrelated to the type of stimulus material are appropriately controlled. These results provide evidence that spatial and nonspatial working memory may not be mediated, respectively, by mid-dorsolateral and mid-ventrolateral regions of the frontal lobe, as widely assumed, and support the alternative notion that specific regions of the lateral prefrontal cortex make identical executive functional contributions to both spatial and nonspatial working memory.