Signal and noise characteristics of SSFPFMRI: A comparison with GRE at multiple field strengths
Signal and noise characteristics of SSFPFMRI: A comparison with GRE at multiple field strengths
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DOI：
10.1016/j.neuroimage.2007.06.024
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发表时间：
2007-10-01
期刊：
影响因子：
5.7
通讯作者：
Wiggins, Christopher J.
中科院分区：
文献类型：
--
作者：
Miller, Karla L.;Smith, Stephen M.;Wiggins, Christopher J.
最近的工作已经提出使用稳态自由进动（SSFP）作为获取功能MRI （FMRI）数据的传统方法的替代方法。SSFP的对比机制可能与传统FM RI信号有关，但信号变化的细节可能在重要方面有所不同。SSFP中的功能对比被认为是由几种不同的机制造成的，这些机制可能在不同程度上取决于实验中使用的具体参数。特别是，信号动力学可能会因序列是否配置为在SSFP过渡带或通带中扫描而有所不同。这项工作描述了通过比较SSFP数据和传统的梯度回忆回波（GRE）数据来探索SSFP FMRI信号变化的来源的实验。在一定范围的磁场强度和重复次数下获取数据，用于过渡带和通带方法。SSFP和GRE的信号特性有显著差异，证实了SSFP的功能对比来源不同。此外，时间噪声特性也有显著差异，这对SSFP FMRI序列优化具有重要意义。(c) 2007爱思唯尔公司版权所有。
Recent work has proposed the use of steady-state free precession (SSFP) as an alternative to the conventional methods for obtaining functional MRI (FMRI) data. The contrast mechanism in SSFP is likely to be related to conventional FM RI signals, but the details of the signal changes may differ in important ways. Functional contrast in SSFP has been proposed to result from several different mechanisms, which are likely to contribute in varying degrees depending on the specific parameters used in the experiment. In particular, the signal dynamics are likely to differ depending on whether the sequence is configured to scan in the SSFP transition band or passband. This work describes experiments that explore the source of SSFP FMRI signal changes by comparing SSFP data to conventional gradient-recalled echo (GRE) data. Data were acquired at a range of magnetic field strengths and repetition times, for both transition band and passband methods. The signal properties of SSFP and GRE differ significantly, confirming a different source of functional contrast in SSFP. In addition, the temporal noise properties are significantly different, with important implications for SSFP FMRI sequence optimisation. (c) 2007 Elsevier Inc. All rights reserved.