Gas-phase formation of large neutral alkaline-earth metal tryptophan complexes
Gas-phase formation of large neutral alkaline-earth metal tryptophan complexes
复制标题
DOI：
10.1016/j.jasms.2008.04.028
复制
发表时间：
2008-07-01
影响因子：
3.2
通讯作者：
Arndt, Markus
中科院分区：
文献类型：
--
作者：
Marksteiner, Markus;Haslinger, Philipp;Arndt, Markus
我们报告的第一次观察到孤立的大中性金属氨基酸络合物，如色氨酸（n）Me（k），与Me = Ca，Ba，Sr，簇组合覆盖n = 1. 33，k = 0.. 2和质量超过6500 u。在团簇混合通道内，用紫外激光解吸碱土金属盐和色氨酸的混合粉末产生团簇束。使用真空紫外光电离，然后通过飞行时间质谱检测粒子。通过确定与金属原子的包含相关的结合能的增益，在分子动力学模拟中证实了金属氨基酸簇在纯氨基酸簇上的增强的稳定性。
We report on the first observation of isolated large neutral metal amino acid complexes such as Trp(n)Me(k), with Me = Ca, Ba, Sr,.cluster combinations covering n = 1... 33, k = 0..2 and masses beyond 6500 u. The cluster beam is generated using UV laser desorption from a mixed powder of alkaline-earth metal salts and tryptophan inside a cluster mixing channel. The particles are detected using VUV photoionization followed by time-of-flight mass spectroscopy. The enhanced stability of metal amino acid clusters over pure amino acid clusters is substantiated in molecular dynamics simulations by determining the gain in binding energy related to the inclusion of the metal atoms.