IgG4 Disease: Is It or Isn't It?
IgG4 Disease: Is It or Isn't It?
复制标题
IgG4 疾病：是还是不是？
DOI：
10.1097/wno.0000000000000446
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发表时间：
2017
期刊：
影响因子：
--
通讯作者：
MacIntosh,PeterW
中科院分区：
文献类型：
--
作者：
Jones,ScottT;Ali,MohsinH;Lin,AmyY;Moss,HeatherE;Srinivasan,Ashok;MacIntosh,PeterW
一位58岁女性，有反复发作的左侧特发性眼眶炎（IOI）病史，在急诊室接受评估，有右眼注射、恐惧、疼痛和视力下降1天的病史。右眼以前从未受到影响。她的左眼因陈旧性IOI相关的后葡萄膜炎和黄斑瘢痕形成而长期视力不佳。大约20年前，她患上了严重的过敏症和哮喘，这与她的左IOI的发病时间一致。10年前，她曾在另一家医疗机构对IOI进行过广泛的评估，包括淋巴结、鼻窦和左泪腺活检，但没有发现炎症的具体原因。她定期服用皮质类固醇治疗过敏和眼睑肿胀，症状和体征有所改善。过敏症专科医生曾尝试过敏脱敏，但患者因发生过敏反应而失败。在我们的检查中，患者的生命体征正常。右眼最佳矫正视力为20/50，左眼为20/200。使用Ishihara板的色觉右眼为7/11，左眼为0/11。由于虹膜粘连，两个瞳孔都不规则;有一个相对的左侧传入瞳孔缺陷。颅神经检查正常。眼外运动充分;眼球运动无疼痛。Hertel眼球突出测量值为右侧28 mm，左侧29 mm，双侧眼球后移阻力中等。上眼睑和下眼睑明显水肿，上眼睑内侧皮肤上有黄色斑块（图1），但触诊未发现肿块。裂隙灯检查显示，右眼有明显的结膜充血、中度角膜水肿、弥漫性点状上皮糜烂（星状模式，对应于内皮纹）、明显的前房无色素细胞和1 mm前房积脓。右眼底正常。左眼角膜透明。有一些虹膜粘连，但没有活动性眼内炎症的迹象;后房型人工透镜定位良好。左眼检眼镜检查显示视乳头周围萎缩和黄斑纤维化，与消退的后节炎症一致。
A58-year-old woman with a history of presumed, recurrent left idiopathic orbital inflammation (IOI) was evaluated in the emergency room with a 1-day history of right eye injection, photophobia, pain, and decreased vision. The right eye had never been affected previously. Her left eye had chronically poor vision from old IOI-associated posterior uveitis and macular scarring. She had developed severe allergies and asthma approximately 20 years previously that had coincided with the onset of her left IOI. Ten years ago, she had had an extensive evaluation for IOI, including lymph node, sinus, and left lacrimal gland biopsies at another medical facility that had revealed no specific cause for the inflammation. She had taken corticosteroids periodically for her allergies and eyelid swelling with improvement in symptoms and signs. An allergist had attempted allergy desensitization, but the patient had failed this treatment due to development of anaphylaxis. On our examination, the patient had normal vital signs. Her best-corrected visual acuity was 20/50, right eye, and 20/200, left eye. Color vision using Ishihara plates was 7/11 with the right eye and 0/11 with the left. Both pupils were irregular due to iris synechiae; there was a left relative afferent pupillary defect. Cranial nerve examination was normal. Extraocular movements were full; there was no pain with eye movement. Hertel exophthalmometry was 28 mm on the right and 29 mm on the left, with moderate resistance to retropulsion bilaterally. There was marked upper and lower eyelid edema with yellow plaques on the medial upper eyelid skin (Fig. 1), but palpation revealed no masses. On slit-lamp examination, the right eye had marked conjunctival injection, moderate corneal edema, diffuse punctate epithelial erosions in a stellate pattern that corresponded to endothelial striae, marked anterior chamber nonpigmented cells, and a 1-mm hypopyon. The right fundus appeared normal. The left eye had a clear cornea. There were a few iris synechiae, but no signs of active intraocular inflammation; a posterior chamber intraocular lens was well positioned. Ophthalmoscopy of the left eye revealed peripapillary atrophy and macular fibrosis consistent with resolved posterior segment inflammation.
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影响因子：
1.6
作者：
London J;Martin A;Soussan M;Badelon I;Gille T;Uzunhan Y;Giroux-Leprieur B;Warzocha U;Régent A;Galatoire O;Dhote R;Abad S
通讯作者：
Abad S
与全身性 IgG4 疾病相关的眼眶坏死性黄色肉芽肿
影响因子：
3.3
作者：
Kamaljeet Singh;K. Rajan;C. Eberhart
通讯作者：
C. Eberhart
眼眶假瘤在小儿葡萄膜炎鉴别诊断中的应用。
影响因子：
1.2
作者：
J. Bloom;E. Graviss;B. J. Byrne
通讯作者：
B. J. Byrne
儿童期特发性炎性眼眶假瘤。
DOI：
--
发表时间：
1978
期刊：
A M A Archives of Ophthalmology
影响因子：
--
作者：
L. Mottow;F. Jakobiec
通讯作者：
F. Jakobiec
DOI：
10.3109/01676830.2013.842252
发表时间：
2014-01-01
影响因子：
1.1
作者：
Verdijk, Robert M.;Heidari, Pegah;Paridaens, Dion
通讯作者：
Paridaens, Dion