Phenotypic characteristics associated with slow gait speed in idiopathic pulmonary fibrosis
Phenotypic characteristics associated with slow gait speed in idiopathic pulmonary fibrosis
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DOI：
10.1111/resp.13213
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发表时间：
2018-05-01
期刊：
影响因子：
6.9
通讯作者：
Man, William D. -C.
中科院分区：
文献类型：
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作者：
Nolan, Claire M.;Maddocks, Matthew;Man, William D. -C.
背景和目的通常步态速度超过 4m (4MGS) 是老年人的一项既定功能表现测量，可一致预测不良健康结果，但特发性肺纤维化 (IPF) 的数据很少。我们评估了 4MGS 的可靠性、其与既定结果测量的关系及其对肺康复的反应性。方法在四个前瞻性 IPF 队列中，确定了 4MGS 观察者间 (n=46) 和重测 (n=46) 可靠性、同时有效性 (n=65 和 n=62) 和反应性 (n=60)。所有患者的表型特征根据慢 4MGS 分层（
Background and objectiveUsual gait speed over 4m (4MGS) is an established functional performance measure in older adults that consistently predicts adverse health outcomes, but few data exist in idiopathic pulmonary fibrosis (IPF). We assessed the reliability of 4MGS, its relationship with established outcome measures and its responsiveness to pulmonary rehabilitation.MethodsIn four prospective IPF cohorts, 4MGS inter-observer (n=46) and test-retest (n=46) reliability, concurrent validity (n=65 and n=62) and responsiveness (n=60) were determined. The phenotypic characteristics of all patients stratified according to slow 4MGS (