SEPARATION OF OVERLAPPING SPECTRA FROM EVOLVING SYSTEMS USING FACTOR-ANALYSIS .2. AMPHOTERICIN-B IN AQUEOUS PROPANOL AND IN AQUEOUS LAUROYL SUCROSE
SEPARATION OF OVERLAPPING SPECTRA FROM EVOLVING SYSTEMS USING FACTOR-ANALYSIS .2. AMPHOTERICIN-B IN AQUEOUS PROPANOL AND IN AQUEOUS LAUROYL SUCROSE
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DOI：
10.1016/0301-4622(94)00030-1
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发表时间：
1994-07-01
影响因子：
3.8
通讯作者：
GRUDA, I
中科院分区：
文献类型：
--
作者：
CHAPADOS, C;BARWICZ, J;GRUDA, I
基于因子分析的方法被用来分离的光谱的各个物种的实验吸收光谱从固定量的阿替西霉素B溶解在水溶液中获得。在丙醇水溶液和月桂酰蔗糖水溶液中，确定了五种：两种单体和三种聚集体。虽然两种介质中不同物质的光谱相似，但两种系统的强度特征却截然不同，并可用于表征它们。
A method based on factor analysis is used to separate the spectra of individual species from the experimental absorption spectra obtained from a fixed amount of amphotericin B dissolved in aqueous solutions. In aqueous propanol solutions and in aqueous lauroyl sucrose solutions, five species are identified: two monomers and three aggregates. Although the spectra of the different species in the two media are similar, the intensity signatures of the two systems are quite different and serve to characterize them.