The large-scale neural network for spatial attention displays multifunctional overlap but differential asymmetry
The large-scale neural network for spatial attention displays multifunctional overlap but differential asymmetry
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DOI：
10.1006/nimg.1999.0408
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发表时间：
1999-03-01
期刊：
影响因子：
5.7
通讯作者：
Mesulam, MM
中科院分区：
文献类型：
--
作者：
Kim, YH;Gitelman, DR;Mesulam, MM
功能磁共振成像（fMRI）被用来确定两种类型的内隐视觉空间注意转移激活的脑区：一种基于外源性空间启动和其他中央凹提出的线索，内源性调节的空间预期的方向。在先前表征的注意力网络的皮质和皮质下成分中观察到激活，即额叶眼区、后顶叶皮质、扣带回、壳核和丘脑。另外的激活发生在前额叶、背外侧前额叶皮质、颞中回和颞下回的颞枕皮质、辅助运动区和小脑。直接比较显示，两个任务导致的激活位置几乎完全重叠。然而，空间启动任务显示出更明显的顶叶激活的不对称性，并联合分析表明，该地区的后顶叶皮层共同激活的两个任务是在右半球更广泛。此外，后顶叶和颞枕叶的激活更明显的内源性注意转移的任务。结果表明，外源性（基于空间启动）和内源性（基于预期提示）的注意转移是由一个共同的网络皮层和皮层下区域。然而，这两个任务之间的差异，特别是在程度上的不对称性，表明该网络内的激活模式可能会显示出变化，反映了注意力任务的特定属性。(C)北京：科学出版社.
Functional magnetic resonance imaging (fMRI) was used to determine the brain regions activated by two types of covert visuospatial attentional shifts: one based on exogenous spatial priming and the other on foveally presented cues which endogenously regulated the direction of spatial expectancy. Activations were seen in the cortical and subcortical components of a previously characterized attentional network, namely, the frontal eye fields, posterior parietal cortex, the cingulate gyrus, the putamen, and the thalamus, Additional activations occurred in the anterior insula, dorsolateral prefrontal cortex, temporo-occipital cortex in the middle and inferior temporal gyri, the supplementary motor area, and the cerebellum. Direct comparisons showed a nearly complete overlap in the location of activations resulting from the two tasks. However, the spatial priming task displayed a more pronounced rightward asymmetry of parietal activation, and a conjunction analysis showed that the area of posterior parietal cortex jointly activated by both tasks was more extensive in the right hemisphere. Furthermore, the posterior parietal and temporo-occipital activations were more pronounced in the task of endogenous attentional shifts. The results show that both exogenous (based on spatial priming) and endogenous (based on expectancy cueing) shifts of attention are subserved by a common network of cortical and subcortical regions. However, the differences between the two tasks, especially in the degree of rightward asymmetry, suggests that the pattern of activation within this network may show variations that reflect the specific attributes of the attentional task. (C) 1999 Academic Press.