C3123A polymorphism of the angiotensin II type 2 receptor gene and salt sensitivity in healthy Japanese men
C3123A polymorphism of the angiotensin II type 2 receptor gene and salt sensitivity in healthy Japanese men
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DOI：
10.1038/sj.jhh.1002007
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发表时间：
2006-06-01
影响因子：
2.7
通讯作者：
Muramatsu, M.
中科院分区：
文献类型：
--
作者：
Miyaki, K.;Hara, A.;Muramatsu, M.
我们的横断面研究表明，血管紧张素II 2型受体（AGTR2）3123A等位基因是一个重要的决定因素的血压反应饮食中的盐摄入量在中年日本男性。虽然未来的研究需要阐明AGTR2基因型和血压之间的关联，饮食中的盐摄入量的前瞻性研究和AGTR2基因和盐敏感性的机制，它可以说，AGTR2基因型是一个潜在的有用的盐敏感性的遗传标记。
Our cross-sectional study shows that the angiotensin II type 2 receptor (AGTR2) 3123A allele is an important determinant of the blood pressure response to dietary salt intake in middle-aged Japanese men. Although future research is required to elucidate for the association between AGTR2 genotype and the blood pressure response to dietary salt intake in prospective studies and for the mechanisms of the AGTR2 gene and salt sensitivity, it can be said that the AGTR2 genotype is a potentially useful genetic marker of salt sensitivity.