Determination of Human Anticytokine Autoantibody Profiles Using a Particle-Based Approach
Determination of Human Anticytokine Autoantibody Profiles Using a Particle-Based Approach
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DOI：
10.1007/s10875-011-9621-8
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发表时间：
2012-04-01
影响因子：
9.1
通讯作者：
Browne, Sarah K.
中科院分区：
文献类型：
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作者：
Ding, Li;Mo, Allen;Browne, Sarah K.
背景抗细胞因子自身抗体可引起多种人类疾病，从纯红细胞再生障碍到获得性免疫缺陷。快速、简单和负担得起的检测和监测这些抗体是必不可少的。我们试图开发一种快速、灵敏、特异的可重复检测方法，能够同时检测小体积的多种抗细胞因子自身抗体（
Background Anticytokine autoantibodies cause numerous human diseases, ranging from pure red cell aplasia to acquired immunodeficiencies. Rapid, simple, and affordable detection and monitoring of these antibodies is essential. We sought to develop a standardizable assay that is rapid, sensitive, and specific and able to simultaneously detect multiple anticytokine autoantibodies in small volumes (