(4R,7S)-2-Amino-4-(3,4-dimeth-oxy-phen-yl)-5-oxo-7-phenyl-5,6,7,8-tetra-hydro-4H-chromene-3-carbonitrile monohydrate.
(4R,7S)-2-Amino-4-(3,4-dimeth-oxy-phen-yl)-5-oxo-7-phenyl-5,6,7,8-tetra-hydro-4H-chromene-3-carbonitrile monohydrate.
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(4R,7S)-2-氨基-4-(3,4-二甲氧基-苯基)-5-氧代-7-苯基-5,6,7,8-四氢-4H-色烯-
DOI：
10.1107/s1600536811056285
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Ou,Yang-Bing
中科院分区：
文献类型：
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作者：
Sun,Rong;Wu,Dong-Dong;Wang,Ke;Huang,Wei;Ou,Yang-Bing
以3，4-二甲氧基苯甲醛、丙二腈和5-苯基环己烷-1，3-二酮为原料，经酯化反应制得标题化合物C24 H22 N2 O 4·H2O。环己基和吡喃环分别显示半船和V形构象。苯环平面与苯环平面之间的二面角为30.67（9）°。 有机分子通过分子间的N-H-N和N-H-O氢键稳定在平行于bc平面的二维网络中。
The title compound, C24H22N2O4·H2O, was obtained by the reaction of 3,4-dimethoxybenzaldehyde, malononitrile and 5-phenylcyclohexane-1,3-dione. The cyclohexyl and pyran rings show half-boat and V-shaped conformations, respectively. The dihedral angle between the phenyl and benzene ring planes is 30.67 (9)°. The organic molecules are packed in a two-dimensional network parallel to the bc plane stabilized by intermolecular N—H⋯N and N—H⋯O hydrogen bonds.