EVALUATION OF AGE-SPECIFIC VACCINATION STRATEGIES
EVALUATION OF AGE-SPECIFIC VACCINATION STRATEGIES
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DOI：
10.1016/0040-5809(84)90016-9
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发表时间：
1984-01-01
影响因子：
1.4
通讯作者：
DIETZ, K
中科院分区：
文献类型：
--
作者：
KATZMANN, W;DIETZ, K
在母源抗体和疫苗免疫力呈指数衰减的假设下，明确确定了特定年龄接种策略和零感染率的易感人群在总人群中的比例。这一比例的倒数值决定了通过相应的战略可以根除的感染的最大繁殖率。对于一生中的单次接种，确定了最佳年龄，在此年龄，易感者的比例达到最低。探讨学龄期1次复种的效果。
Under the assumption that maternal antibodies and vaccine immunity decay exponentially, the proportions of susceptibles in the total population for given age-specific vaccination strategies and zero infection incidence were determined explicitly. The reciprocal value of such a proportion determined the maximum reproductive rate of an infection which could be eradicated by the corresponding strategy. For a single vaccination during life, the optimum age was determined, for which the proportion of susceptibles reached a minimum. The effect of 1 revaccination during school age was explored.