Accelerated Diffusion Spectrum Imaging in the Human Brain Using Compressed Sensing
Accelerated Diffusion Spectrum Imaging in the Human Brain Using Compressed Sensing
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DOI：
10.1002/mrm.23064
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发表时间：
2011-11-01
影响因子：
3.3
通讯作者：
Marinelli, Luca
中科院分区：
文献类型：
--
作者：
Menzel, Marion I.;Tan, Ek T.;Marinelli, Luca
提出了一种基于压缩感知的扩散谱成像加速方法。该方法既可以减少弥散谱成像的采集时间而不丢失关键信息，也可以提高弥散空间的分辨率而不增加扫描时间。与并行成像不同，压缩感知可以应用于在空间域之外的域中重建亚奈奎斯特采样数据集。对二维和三维光纤交叉进行了仿真，系统地评估了不同欠采样模式（随机、高斯、泊松盘）和不同加速因子对径向和轴向扩散信息的压缩传感重建效果。在健康志愿者的大脑中进行实验，其中扩散空间用不同的采样模式欠采样，并使用压缩传感重建。扩散特性的基本信息，如方向分布函数，扩散系数和峰度被保存到R 5 = 4的加速因子。Magn Reson Med 66：1226-1233，2011. (C)2011 Wiley Periodicals，Inc.
We developed a novel method to accelerate diffusion spectrum imaging using compressed sensing. The method can be applied to either reduce acquisition time of diffusion spectrum imaging acquisition without losing critical information or to improve the resolution in diffusion space without increasing scan time. Unlike parallel imaging, compressed sensing can be applied to reconstruct a sub-Nyquist sampled dataset in domains other than the spatial one. Simulations of fiber crossings in 2D and 3D were performed to systematically evaluate the effect of compressed sensing reconstruction with different types of undersampling patterns (random,gaussian, Poisson disk) and different acceleration factors on radial and axial diffusion information. Experiments in brains of healthy volunteers were performed, where diffusion space was undersampled with different sampling patterns and reconstructed using compressed sensing. Essential information on diffusion properties, such as orientation distribution function, diffusion coefficient, and kurtosis is preserved up to an acceleration factor of R 5 = 4. Magn Reson Med 66: 1226-1233, 2011. (C) 2011 Wiley Periodicals, Inc.