A periodized training attenuates thigh intermuscular fat and improves muscle quality in patients with knee osteoarthritis: results from a randomized controlled trial
A periodized training attenuates thigh intermuscular fat and improves muscle quality in patients with knee osteoarthritis: results from a randomized controlled trial
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DOI：
10.1007/s10067-019-04892-9
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发表时间：
2020-04-01
影响因子：
3.4
通讯作者：
Mattiello, Stela Marcia
中科院分区：
文献类型：
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作者：
de Almeida, Aline Castilho;Aily, Jessica Bianca;Mattiello, Stela Marcia
目的分析14周周期性循环训练（CT）对膝骨关节炎（KOA）患者大腿肌间脂肪和肌肉质量（单位面积力量）的影响。方法选择61例KOA 2级和3级、40-65岁、BMI < 30 kg/m2的受试者，随机分为3组：CT组、常规力量训练（ST）组和教育方案（EP）组。CT和ST方案包括每周进行3次的14周训练方案。CT组进行运动分层为轻，中度，和激烈的，逐步安排在电路模型。ST组进行常规力量训练，EP组每月参加两次关于健康生活方式的讲座。对大腿肌间脂肪（计算机断层扫描）、膝关节伸展最大等长随意收缩（MIVC）和肌肉质量（膝关节伸展MIVC/肌肉质量横截面积）进行基线和随访（第0周和第14周）评价。结果与EP组相比，仅CT组大腿肌间脂肪显著减少（p = 0.003），第14周时的数值显著降低（p = 0.032）。与EP相比，两个训练组在第14周的肌肉质量面积（CT p=0.002，ST p=0.008）和膝关节伸展MIVC增量（CT p= 0.033，ST p=0.019）显著增加，肌肉质量增加（p = 0.004和0.042）。结论14周分期CT治疗可减少膝关节骨性关节炎患者大腿肌间脂肪，改善肌肉质量。
Objective To analyze the influence of a 14-week periodized circuit training (CT) protocol on thigh intermuscular fat and muscle quality (force per unit area of lean tissue) in patients with knee osteoarthritis (KOA). Design Randomized controlled trial Methods Sixty-one selected participants with KOA grades 2 and 3, 40-65 years old, and BMI < 30 kg/m(2) were randomized into three groups: CT, conventional strength training (ST), and educational protocol (EP). The CT and ST protocols consisted of 14-week training protocols conducted 3 times a week. The CT group performed exercises stratified as light, moderate, and intense, arranged progressively in a circuit model. The ST group performed conventional strength exercises, and the EP group participated in lectures twice a month about healthy lifestyles. Baseline and follow-up (week 0 and week 14) evaluations were conducted for thigh intermuscular fat (computed tomography), knee extension maximal isometric voluntary contraction (MIVC), and muscle quality (knee extension MIVC/muscle mass cross-sectional area). Results Only the CT group presented significant reductions in thigh intermuscular fat (p = 0.003) and significantly lower values in week 14 compared with the EP (p = 0.032). Both trained groups presented significant increases in muscle mass area (p=0.002 for CT and p=0.008 for ST) and increments in knee extension MIVC (p=0,033 for CT nd p=0.019 for ST) in week 14 compared with the EP and increases in muscle quality (p = 0.004 and 0.042). Conclusion It can be concluded that a 14-week periodized CT protocol attenuates thigh intermuscular fat and improves muscle quality in patients with KOA.