Development of Heterotypic Combinations of Dissociated Embryonic Chick Cells.∗
Development of Heterotypic Combinations of Dissociated Embryonic Chick Cells.∗
复制标题
离解胚胎鸡细胞异型组合的开发。*
DOI:
10.3181/00379727-92-22495
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发表时间:
1956
影响因子:
--
通讯作者:
Paul Weiss
中科院分区:
文献类型:
--
作者:
Paul Weiss
Summary 1. The behavior in vitro of dissociated and reaggregated mesonephric and limb-bud cells of the early chick embryo was studied in heterotypic, isochronic and heterochronic combinations, 2. Under the conditions examined, all cell types incorporated in the cell suspensions reappeared eventually in the aggregates to form tissue-like groupings that developed in accordance with their tissues of origin. 3. Manifestation of the characteristic histogenetic activity by cells of a given type in a heterotypic combination decreased in proportion to their share in the total population. If present below a certain liminal proportion, the cells did not reconstitute their typical tissue fabric, although equal amounts, when cultured separately, would differentiate histotypically.