Development of Heterotypic Combinations of Dissociated Embryonic Chick Cells.∗

Development of Heterotypic Combinations of Dissociated Embryonic Chick Cells.∗
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离解胚胎鸡细胞异型组合的开发。*

DOI:
10.3181/00379727-92-22495
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发表时间:
1956
影响因子:
--
通讯作者:
Paul Weiss
Paul Weiss
中科院分区:
--
文献类型:
--
作者:
Paul Weiss

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摘要1。在异性型,等型和异chronic组合中研究了早期雏鸡胚胎的分解和重现的中肾和肢体 - 肢体细胞的体外行为。聚集体形成基于其原产组织开发的组织样分组。 3。在异型组合中通过给定类型的细胞表现出特征性组织遗传活性的表现,其与其在总人群中的份额成比例降低。如果以下是一定的界限比例,则细胞不会重建其典型的组织织物,尽管当分别培养时相等的量会在组织型上区分。
Summary 1. The behavior in vitro of dissociated and reaggregated mesonephric and limb-bud cells of the early chick embryo was studied in heterotypic, isochronic and heterochronic combinations, 2. Under the conditions examined, all cell types incorporated in the cell suspensions reappeared eventually in the aggregates to form tissue-like groupings that developed in accordance with their tissues of origin. 3. Manifestation of the characteristic histogenetic activity by cells of a given type in a heterotypic combination decreased in proportion to their share in the total population. If present below a certain liminal proportion, the cells did not reconstitute their typical tissue fabric, although equal amounts, when cultured separately, would differentiate histotypically.