Larger amounts of visceral adipose tissue in Asian Americans
Larger amounts of visceral adipose tissue in Asian Americans
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DOI：
10.1038/oby.2001.49
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发表时间：
2001-07-01
期刊：
影响因子：
--
通讯作者：
Gallagher, D
中科院分区：
文献类型：
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作者：
Park, YW;Allison, DB;Gallagher, D
目的：过多的内脏脂肪组织（VAT）被认为是冠心病和2型糖尿病发展的重要危险因素。一些研究报告称，与白人相比，非洲裔美国人的增值税较低。由于对亚洲人的VAT水平知之甚少，我们比较了亚裔美国人与欧洲裔美国人的全身VAT。研究方法和程序：使用全身多层磁共振成像测量54名妇女的VAT（18名亚裔美国人，36名欧洲裔美国人）和53名男性（19名亚裔美国人，34名欧洲裔美国人），体重指数（以千克/平方米测量）< 30。结果：在校正年龄和全身脂肪后，亚裔美国妇女的对数转换增值税高于欧美妇女（p < 0.05）。有一个显着的年龄由种族相互作用，这样的种族差异增值税是最明显的超过30岁。没有差异，增值税可以检测到亚裔美国人和欧洲裔美国人之间，即使调整潜在的协变量，包括总adiposity.Discussion：这些数据是第一个证明更高的增值税金额在健康的亚裔美国人，一项发现，表明规范增值税值或标准来自白人可能不适用于亚洲人。
Objective: Excess visceral adipose tissue (VAT) is recognized as an important risk factor for the development of coronary heart disease acid type 2 diabetes. Several studies have reported less VAT in African Americans compared with whites. As little is known about the levels of VAT in Asians, we compared whole-body VAT in Asian Americans with European Americans.Research Methods and Procedures: VAT was measured using whole-body multislice magnetic resonance imaging in 54 women(18 Asian Americans, 36 European Americans) and 53 men (19 Asian Americans, 34 European Americans) with body mass index (measured in kilograms per square meter) < 30. Data were analyzed by multiple regression modeling.Results: Asian American women had higher log-trans formed VAT compared with European American women (p < 0.05), after adjusting for age and total body fat. There was a significant age by race interaction such that race differences in VAT were most evident over the age of 30 years. No differences in VAT could be detected between Asian American and European American men, even after adjusting for potential covariates, including total adiposity.Discussion: These data are the first to demonstrate higher amounts of VAT in healthy Asian Americans, a finding that suggests normative VAT values or standards derived from whites may not be applicable to Asians.