Preparatory brain activity and anticipatory postural adjustments accompanied by externally cued weighted-rapid arm rise task in non-specific chronic low back pain patients and healthy subjects
Preparatory brain activity and anticipatory postural adjustments accompanied by externally cued weighted-rapid arm rise task in non-specific chronic low back pain patients and healthy subjects
复制标题
非特异性慢性腰痛患者和健康受试者的准备性大脑活动和预期姿势调整伴随外部提示加权快速手臂上升任务
作者：
M. Sadeghi;S. Talebian;G. Olyaei;B. Attarbashi Moghadam
目的：皮质重组是腰痛患者预期体位调节功能受损的最可能机制之一。为了明确皮质运动神经生理学的变化，采用肌电图（EMG）和脑电图（EEG）评估APAs。方法29例非特异性腰痛患者和健康受试者在刺激间隔2 s内对听觉命令性刺激和警告性刺激进行单侧快速手臂运动。爆发时的活动与双侧横腹/内斜肌（TrA/IO）前三角肌的活动有关，也与左侧体位肌的活动有关，包括腹直肌、外斜肌（E.O）、竖脊肌和腓肠肌内侧头（Gc.M）。头皮EEG记录随机负变异电位（CNV），分析受者工作特征曲线下面积（AUC）。结果在LBP患者中，E.O和双侧TrA/IO的发病时间明显延迟，而Gc的发病时间明显提前。M （P < 0.05）。LBP患者的CNV参数明显高于LBP患者（P < 0.01）。仅左侧TrA/IO和eo肌AUC显著（P < 0.05）。结论腰痛患者CNV波幅增加，APA发病时间重新组织，躯干延迟，远端提前。这些发现支持了LBP患者大脑皮层重组活动的假说。
ObjectiveCortical reorganization is one of the most plausible mechanisms underlying impairment of anticipatory postural adjustments (APAs) in low back pain (LBP) patients. In order to clarify changes in corticomotor neurophysiology, APAs were assessed by using electromyography (EMG) and electroencephalography (EEG).MethodsAn equal number (29) of nonspecific LBP patients and healthy subjects performed unilateral rapid arm movements in response to auditory imperative stimulus preceded by warning stimulus within 2 s interstimulus interval. Burst onset activity was calculated in relation to the activity of anterior deltoid for bilateral transverse abdominis/internal oblique (TrA/IO), and also postural muscles on left side, including rectus abdominis, external oblique (E.O), erector spinae and medial head of gastrocnemius (Gc.M). Contingent negative variation (CNV) potentials were recorded by scalp EEG, and the area under receiver operating characteristic curve (AUC) was analyzed.ResultsIn LBP patients, there was a significant onset delay for E.O and bilateral TrA/IO, but a significant earlier activity for Gc.M (for both P < 0.05). The CNV parameters were considerably greater in LBP patients (P < 0.01). The AUC was significant just for left TrA/IO and E.O muscles (P < 0.05).ConclusionsThe CNV amplitudes were increased, and APA onset times re-organized to be delayed at the trunk and early at the distal limb in LBP cases. These findings support the hypothesis about reorganized activity of cerebral cortex in LBP patients.
影响因子：
3.2
作者：
Whitney, SL;Wrisley, DM;Furman, JM
通讯作者：
Furman, JM