Alcohol consumption and the risk of alcohol related cirrhosis in women.

Alcohol consumption and the risk of alcohol related cirrhosis in women.
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女性饮酒和酒精相关肝硬化的风险。

DOI:
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发表时间:
1987
影响因子:
--
通讯作者:
S. MacMahon
S. MacMahon
中科院分区:
医学1区
文献类型:
--
作者:
R. Norton;R. Batey;T. Dwyer;S. MacMahon

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在一项病例对照研究中,对不同饮酒水平的女性肝硬化的风险进行了估计。数据来自41名首次诊断为肝硬化的女性,她们没有非酒精相关肝硬化的证据;每个病例采访了三名匹配的对照。肝硬化的风险显着增加,检测到消费水平之间的41和60克每天;高于这个水平的剂量反应关系进行了观察。肝硬化的风险似乎不受其他营养因素或肝病史或使用肝毒性药物的影响。1%的澳大利亚妇女每天饮酒超过40克,但超过90%的肝硬化妇女饮酒量达到这一水平。预防性干预措施,以减少酒精消费量的一小群妇女谁消费超过40克,每天有可能大大减少酒精相关肝硬化的发病率。
The risks in women of cirrhosis with a likely primary alcohol aetiology were estimated for various levels of alcohol consumption in a case-control study. Data were obtained from 41 women with a first diagnosis of cirrhosis who had no evidence of non-alcohol-related cirrhosis; three matched controls were interviewed for each case. Significant increases in the risk of cirrhosis were detected at levels of consumption between 41 and 60 g daily; above this level a dose-response relation was observed. The risk of cirrhosis did not appear to be influenced by other nutritional factors or history of liver disease or use of hepatotoxic drugs. One per cent of Australian women consume more than 40 g alcohol daily, yet more than 90% of women identified with cirrhosis consumed alcohol at this level. Preventive interventions to reduce alcohol consumption in the small group of women who consume more than 40 g daily have the potential to reduce substantially the incidence of alcohol related cirrhosis.
初级卫生保健机构中的酒精相关问题:早期干预策略回顾。
DOI: 10.1111/j.1360-0443.1986.tb00291.x
发表时间: 1986
期刊: British journal of addiction
影响因子: --
作者:
Babor,TF;Ritson,EB;Hodgson,RJ
通讯作者: Hodgson,RJ