Familial transmission of suicidal behavior: Factors mediating the relationship between childhood abuse and offspring suicide attempts
Familial transmission of suicidal behavior: Factors mediating the relationship between childhood abuse and offspring suicide attempts
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DOI：
10.4088/jcp.v69n0410
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发表时间：
2008-04-01
影响因子：
5.3
通讯作者：
Brent, David
中科院分区：
文献类型：
--
作者：
Brodsky, Beth S.;Mann, J. John;Brent, David
背景：自我报告的儿童期性虐待与重度抑郁症和自杀行为有关。本研究探讨报告的儿童期虐待和家庭传播的自杀行为和其他相关的危险factors.Method：507后代的271父母先证者与DSM-IV抑郁症进行了比较，根据报告的儿童期虐待史的人口统计学，诊断和临床变量的自杀行为的风险。自我报告和临床访谈的措施评估的历史，童年的身体和性虐待。研究时间为1997年5月至2004年2月。结果：先证者报告的儿童期性虐待与自杀企图、创伤后应激障碍、抑郁症发病早、冲动程度高、子女遭受儿童期性虐待的可能性大有关，但与身体虐待无关。报告的儿童期身体虐待的历史是与更多的终身侵略的后代。结论：报告的儿童期性虐待是父母和后代自杀行为的危险因素。自杀风险的代际传播与性虐待和冲动的家庭传播有关。性虐待不会由受害者直接传给下一代，可能与性虐待相关的家庭动态有关。
Background: Self-reported childhood sexual abuse is associated with major depression and with suicidal behavior. The current study investigates the relationship between reported childhood abuse and the familial transmission of suicidal behavior and other related risk factors.Method: 507 offspring of 271 parent probands with DSM-IV major depressive disorder were compared according to the reported childhood abuse history on demographic, diagnostic, and clinical variables related to risk for suicidal behavior. Both self-report and clinical interview measures assessed history of childhood physical and sexual abuse. The study was conducted from May 1997 to February 2004.Results: Reported childhood sexual abuse, but not physical abuse, in the proband correlated with suicide attempts, posttraumatic stress disorder, earlier onset of major depressive disorder, higher levels of impulsivity, and greater likelihood of childhood sexual abuse in the offspring and was rarely perpetrated by the affected parent. A reported history of childhood physical abuse was related to more lifetime aggression in the offspring.Conclusions: Reported childhood sexual abuse is a risk factor for suicidal behavior in parent and offspring. Transmission of suicide risk across generations is related to the familial transmission of sexual abuse and impulsivity. Sexual abuse is not directly transmitted by the victim to the next generation and may be related to family dynamics related to sexual abuse.