Concept of microbial gatekeepers: Positive guys?
Concept of microbial gatekeepers: Positive guys?
复制标题
DOI：
10.1007/s00253-018-9522-3
复制
发表时间：
2019
期刊：
影响因子：
--
通讯作者：
Jinbo Xiong
中科院分区：
文献类型：
--
作者：
Wenfang Dai;Jiong Chen;Jinbo Xiong
Microorganisms contribute diverse and fundamental roles in biogeochemical processes. In a given microbial community, individuals interact with one another to form complex regulatory networks in which gatekeepers contribute disproportional roles in sustaining stability, dynamics, and function. Owing to the ecological and functional importance of microbial gatekeeper, this review provides an overview on its history, identification, roles, application in biological sciences, and clinical diagnostics. The roles of microbial gatekeepers can be beneficial or detrimental, which depends on our purpose. As the field is rather new, some limitations are raised, and further efforts devoted to solving these concerns are proposed. Collectively, gatekeepers provide promising targets for sustaining and re-establishing a desired microbial community. However, substantial obstacles, such as factors governing gatekeepers, must be overcome to manipulate gatekeepers as positive guys.
