Predictive factors for comorbid psychiatric disorders and their impact on vision-related quality of life in patients with high myopia
Predictive factors for comorbid psychiatric disorders and their impact on vision-related quality of life in patients with high myopia
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DOI：
10.1007/s10792-013-9805-8
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发表时间：
2014-04-01
影响因子：
1.6
通讯作者：
Ohno-Matsui, Kyoko
中科院分区：
文献类型：
--
作者：
Yokoi, Tae;Moriyama, Muka;Ohno-Matsui, Kyoko
确定高度近视患者抑郁和焦虑障碍的发生率以及预测精神并发症发生的因素及其对视觉相关生活质量（VR-QoL）的影响。本文报告205例病理性近视（眼轴长度a/1000元26.50 mm）。抑郁和焦虑障碍的发病率采用医院焦虑和抑郁量表（HADS）测定。VR-QoL由25项国家眼科研究所视觉功能问卷确定。抑郁发生率为22.0%，焦虑发生率为25.9%.无子女是与抑郁症显著相关的唯一因素，既往白内障手术史是与焦虑症显著相关的唯一因素。降低VR-QoL的因素依次为焦虑障碍、最佳眼视力下降、抑郁、女性。受试者对两个HADS陈述的反应“我可以笑，看到事情有趣的一面”和“我可以享受一本好书或广播或电视节目”确定了82.2%的抑郁症患者，“我突然感到恐慌”和“我可以坐下来放松”确定了71.7%的焦虑症患者。22%至26%的高度近视患者患有精神疾病，对他们的VR-QoL产生强烈的负面影响。HADS问卷中的两项陈述可用于筛查高度近视患者的抑郁症或焦虑症。
To determine the incidence of depression and anxiety disorders in patients with high myopia as well as the factors that would predict the development of psychiatric complications and their impact on vision-related quality of life (VR-QoL). Two hundred and five patients with pathologic myopia (axial length a parts per thousand yen26.50 mm) were studied. Incidence of depression and anxiety disorders was determined using the Hospital Anxiety and Depression Scale (HADS). VR-QoL was determined by the 25-item National Eye Institute Visual Function Questionnaire. Incidence of depression was 22.0 % and incidence of anxiety disorder was 25.9 %. Absence of children was the only factor significantly associated with the presence of depression, and a past history of cataract surgery was the only factor significantly associated with the presence of anxiety disorder. Factors which decreased the VR-QoL were in order of importance-anxiety disorder, decreased visual acuity in the best eye, depression, and being female. Responses of the subjects to two HADS statements 'I can laugh and see the funny side of things' and 'I can enjoy a good book or radio or television program' identified 82.2 % of depressed patients, and 'I get sudden feelings of panic' and 'I can sit at ease and feel relaxed' identified 71.7 % of patients with anxiety disorder. Twenty-two to 26 % of highly myopic patients had psychiatric disorders which had a strong negative impact on their VR-QoL. Two statements from the HADS questionnaire can be used to screen highly myopic patients for depression or anxiety disorders.