Calibration Methodology of an Edgeless PET System Prototype.
Calibration Methodology of an Edgeless PET System Prototype.
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DOI：
10.1109/nss/mic42677.2020.9508042
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发表时间：
2020-10
期刊：
影响因子：
--
通讯作者：
Gonzalez AJ
中科院分区：
文献类型：
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作者：
Freire M;Gonzalez-Montoro A;Cañizares G;Berr SS;Vidal LF;Hernandez L;Gonzalez AJ
小动物正电子发射断层扫描（PET）成像中的仪器研究是通过提高时间、空间分辨率和灵敏度来驱动的。传统的PET扫描仪是由多个探测器组成的，这些探测器被放置在圆柱形几何结构中，在横轴平面和轴向平面中它们之间都有间隙。这些间隙降低了灵敏度，并降低了朝向系统视场（FOV）边缘的空间分辨率。为了缓解这些问题，我们设计并验证了一种基于内径为62 mm的单个LYSO瓣环和10个各为26 × 52 mm2的外小平面的无边缘临床前PET系统。闪烁光通过安装在磁场兼容PCB中的硅光电倍增管（SiPM）的行和列读出。本工作的目的是提供一个校准方法，该系统。环的特定设计在模块接合处的光分布（LD）中产生一些不期望的影响，这需要被解决。然而，在校准之后，系统允许正确地检索能量和3D光子撞击位置两者。
Instrumentation research in small animal Positron Emission Tomography (PET) imaging is driven by improving timing, spatial resolution and sensitivity. Conventional PET scanners are built of multiple detectors placed in a cylindrical geometry with gaps between them in both the transaxial and axial planes. These gaps decrease sensitivity and degrade spatial resolution towards the edges of the system field of view (FOV). To mitigate these problems, we have designed and validated an edgeless pre-clinical PET system based on a single LYSO annulus with an inner diameter of 62 mm and 10 outer facets of 26 × 52 mm2 each. The scintillation light is read out using the row and columns of Silicon Photomultipliers (SiPMs) mounted in magnetic-field compatible PCBs. The objective of this work is to provide a calibration method for this system. The particular design of the annulus produces some undesirable effects in the light distributions (LD) at the module joints, which needs to be addressed. Nevertheless, after calibration, the system allows one to properly retrieve both, the energy and 3D photon impact positions.