Distribution trends of gastric polyps: An endoscopy database analysis of 24 121 northern Chinese patients
Distribution trends of gastric polyps: An endoscopy database analysis of 24 121 northern Chinese patients
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胃息肉分布趋势：24 121例中国北方患者内镜数据库分析
DOI：
10.1111/j.1440-1746.2012.07116.x
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发表时间：
2012-07-01
影响因子：
4.1
通讯作者：
Qu, Rui
中科院分区：
文献类型：
--
作者：
Cao, Hailong;Wang, Bangmao;Qu, Rui
背景和目的：传统上最常见的胃息肉是增生性息肉（HP）。然而，在过去的二十年里，胃底腺息肉（FGP）在西方国家大大增加。我们的目的是重新评估和比较2000年和2010年中国北方人群中胃息肉的分布。方法：回顾性分析2000年和2010年我院收治的胃息肉患者的临床资料，并对活检结果进行分析。资料包括患者的年龄、性别、症状、数量、大小、部位、幽门螺杆菌（H. pylori）感染的息肉。结果如下：2000年和2010年分别对6784例和17337例患者进行了食管胃镜检查，诊断为胃息肉的患者分别为68例和183例。H. pylori感染率从54.4%下降到37.7%（P = 0.017）。总的来说，胃息肉的光谱发生了变化（P < 0.001）。HP占28.3%，从48.5%下降到20.8%，腺瘤/癌和炎性息肉也有所下降。FGPs在50.6%中存在，从8.8%增加到66.1%。息肉的位置也随胃体息肉的增多而改变。女性中FGP的比例较高，而腺瘤/腺癌在男性中更常见。年轻和老年患者的分布模式相似。结论：在过去10年中，在中国北方人群中观察到胃息肉的谱变化，这很可能是由于FGP的比例较高。需要进一步的研究来调查原因，并确认它是否会导致中国不同的管理策略。
Background and Aim: Traditionally the most common gastric polyps are hyperplastic polyps (HPs). However, in the last two decades, fundic gland polyps (FGPs) have greatly increased in Western countries. We aimed to re-evaluate and compare the distribution of gastric polyps in a northern Chinese population in 2000 and 2010. Methods: Consecutive patients with gastric polyps detected in 2000 and 2010 were analyzed and biopsies were re-evaluated. Data including patients' age, sex, symptoms and the number, size, location, Helicobacter pylori (H. pylori) infection of polyps were recorded. Results: A total of 6784 and 17 337 patients underwent esophagogastroduodenoscopy in 2000 and 2010, 68 and 183 patients were diagnosed with gastric polyps, respectively. H. pylori infection decreased from 54.4% to 37.7% (P = 0.017). Overall, spectrum of gastric polyps changed (P < 0.001). HPs accounted for 28.3% and decreased from 48.5% to 20.8%, adenoma/carcinoma and inflammatory polyps also decreased. FGPs were present in 50.6% and increased from 8.8% to 66.1%. The location of polyps was also changed with an increase of polyps in gastric corpus. There was a high proportion of FGPs in females, while adenomas/adenocarcinomas were more common in males. The distribution pattern was similar in young and elderly patients. Conclusions: Spectrum change of gastric polyps was observed over the past 10 years in the northern Chinese population most likely due to the higher proportion of FGPs. Further studies are required to investigate the reasons and confirm whether it will lead to a different management strategy in China.