Responses of ganglion cells to repetitive electrical stimulation of the retina
Responses of ganglion cells to repetitive electrical stimulation of the retina
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DOI：
10.1088/1741-2560/4/1/s01
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发表时间：
2007-03-01
影响因子：
4
通讯作者：
Rizzo, Joseph F., III
中科院分区：
文献类型：
--
作者：
Jensen, Ralph J.;Rizzo, Joseph F., III
视网膜神经节细胞(RGC)可以直接或间接(通过视网膜神经网络)被电激活。先前的研究表明，当直接激活时，视网膜节细胞可以跟随高刺激率(>；=200脉冲S(-1))。在目前的研究中，我们调查了视网膜节细胞对神经网络重复刺激的跟踪能力。我们研究了不同脉冲间隔的成对脉冲和不同频率的脉冲串对刺激兔视网膜RGCs的反应(棘波活动)。我们发现RGC对电流脉冲的响应幅度很快(
Retinal ganglion cells (RGCs) can be activated electrically either directly or indirectly (via the retinal neural network). Previous studies have shown that RGCs can follow high stimulus rates (>= 200 pulses s(-1)) when directly activated. In the present study, we investigated how well RGCs can follow repetitive stimulation of the neural network. We studied the responses (spike activity) of RGCs in isolated rabbit retina to stimulation with paired pulses applied at different interpulse intervals and trains of pulses applied at different frequencies. We found that the response amplitude of a RGC to a current pulse applied soon (