Outcomes of femtosecond laser-assisted penetrating keratoplasty
Outcomes of femtosecond laser-assisted penetrating keratoplasty
复制标题
DOI：
10.1016/j.ajo.2008.01.003
复制
发表时间：
2008-05-01
影响因子：
4.2
通讯作者：
Tan, Donald T. H.
中科院分区：
文献类型：
--
作者：
Por, Yong M.;Cheng, Jacob Y. Chuan;Tan, Donald T. H.
目的：评估在穿透性角膜移植术 (PK) 过程中使用飞秒激光环锯供体和受体角膜的结果。设计：前瞻性介入。病例系列。方法：从新加坡国家眼科中心角膜诊所招募患者。我们使用 10-kHZ Femtec（20/10 Perfect Vision，德国海德堡）飞秒激光在人工前房上对供体角膜进行环钻，然后对受体角膜进行环钻。环钻切割是笔直的并且与角膜表面成90度。用 Barrett 超声乳化切碎器直接分离组织桥。然后用双连续缝合将供体纽扣缝合到受体，或者如果存在显着的宿主角膜血管化则采用间断缝合。术后，对视力、屈光度、眼压和光学相干断层扫描（Visante；Carl Zeiss，耶拿，德国）进行了评估。 结果：8 名患者的 8 只眼睛接受了 PK，其病情范围从大疱性角膜病变到疱疹性基质角膜炎引起的角膜疤痕。患者平均随访 9.5 个月。无眼部合并症的患者的最佳矫正视力范围为 20/20 至 20/80。上次检查时的平均柱镜屈光度为 2.56 屈光度 [D]（范围：0.50 至 4.00 D）。除了一例需要剪刀完成环钻的情况外，组织桥被直接解剖。没有遇到与使用 Femtec 激光相关的并发症。结论：Femtec 激光能够可靠地环钻供体和受体角膜进行 PK，具有良好的视觉效果和相对较低的散光度。
PURPOSE: To evaluate outcomes from the use of a femtosecond laser to trephine both donor and recipient corneas during penetrating keratoplasty (PK).DESIGN: Prospective interventional. case series.METHODS: Patients were recruited from the cornea clinic of the Singapore National Eye Centre. We used a 10-kHZ Femtec (20/10 Perfect Vision, Heidelberg, Ger, many) femtosecond laser to perform trephination of the donor cornea on an artificial anterior chamber, followed by trephination of the recipient cornea. Trephination cuts were straight and performed 90 degrees to the corneal surface. Tissue bridges were bluntly separated with a Barrett phaco chopper. The donor button was then sutured to the recipient with double continuous sutures, or interrupted sutures if significant host corneal vascularization was present. Postoperatively, visual acuity, refraction, intraocular pressures, and optical coherence tomography (Visante; Carl Zeiss, Jena, Germany) were evaluated.RESULTS: Eight eyes of eight patients underwent PK for conditions ranging from bullous keratopathy to corneal scarring from herpetic stromal keratitis. Patients were followed up for a mean of 9.5 months. Best-corrected visual acuities of patients with no ocular comorbidity ranged from 20/20 to 20/80. Mean cylindri, cal refractive error at last review was 2.56 diopters [D] (range, 0.50 to 4.00 D). Tissue bridges were bluntly dissected except for one case that required scissors completion of trephination. No complications were encountered related to use of the Femtec laser.CONCLUSION: The Femtec laser reliably trephines both donor and recipient corneas for PK, with good visual outcomes and relatively low degrees of astigmatism.