Can linoleic acid contribute to coronary artery disease?
Can linoleic acid contribute to coronary artery disease?
复制标题
亚油酸会导致冠状动脉疾病吗？
DOI：
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发表时间：
1993
影响因子：
7.1
通讯作者：
N. Balazs
中科院分区：
文献类型：
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作者：
J. Hodgson;M. Wahlqvist;J. Boxall;N. Balazs
在一项对226名接受冠状动脉造影术的患者的横断面研究中，亚油酸的脂肪组织浓度与冠状动脉疾病(CAD)的程度呈正相关。脂肪组织中的亚油酸浓度可以反映这种脂肪酸的摄入量。因此，这些结果表明亚油酸摄入量与冠心病之间存在正相关关系。血小板亚油酸浓度与冠心病也呈正相关。在考虑了混杂因素后，男性血小板中二十碳五烯酸浓度与冠心病呈负相关，女性血小板二十二碳五烯酸浓度与冠心病呈负相关；结果与其他几项研究一致，这些研究表明鱼以及从鱼和鱼油中提取的omega-3脂肪酸可以有益地影响大血管疾病。
The adipose tissue concentration of linoleic acid was positively associated with the degree of coronary artery disease (CAD) in a cross-sectional study of 226 patients undergoing coronary angiography. Linoleic acid concentration in adipose tissue is known to reflect the intake of this fatty acid. These results are therefore indicative of a positive relationship between linoleic acid intake and CAD. The platelet linoleic acid concentration was also positively associated with CAD. After confounding factors were allowed for, the eicosapentaenoic acid concentration in platelets was inversely associated with CAD for men, and the docosapentaenoic acid concentration in platelets was inversely associated with CAD for women; results consistent with several other studies that suggest that fish, and omega-3 fatty acids derived from fish and fish oils, can beneficially influence macrovascular disease.