Diagnosis and Assessment of Pulmonary Arterial Hypertension
Diagnosis and Assessment of Pulmonary Arterial Hypertension
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DOI：
10.1016/j.jacc.2009.04.011
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发表时间：
2009-06-30
影响因子：
24
通讯作者：
Torbicki, Adam
中科院分区：
文献类型：
--
作者：
Badesch, David B.;Champion, Hunter C.;Torbicki, Adam
肺动脉高压的诊断和评估是一个快速发展的领域，疾病的定义、筛查和诊断技术、分期和随访评估都发生了变化。肺动脉高压的定义已经简化，现在是基于现有的证据。在推进成像技术和生物标志物方面取得了实质性进展，这些技术和生物标志物用于筛查患者的疾病，并跟踪他们对治疗的反应。准确评估右心室功能对随访临床病程和治疗反应的重要性得到了充分的认识。随着肺动脉高压新疗法的发展，筛查、及时诊断和准确评估疾病严重程度变得越来越重要。肺动脉高压的明确定义和合理的诊断评估方法的发展以及使用传统和新工具的随访对于从我们不断扩大的治疗设备中获得最大的益处至关重要。[J]中华医学会心脏科杂志2009；54:55-66)(C) 2009
The diagnosis and assessment of pulmonary arterial hypertension is a rapidly evolving area, with changes occurring in the definition of the disease, screening and diagnostic techniques, and staging and follow-up assessment. The definition of pulmonary hypertension has been simplified, and is now based on currently available evidence. There has been substantial progress in advancing the imaging techniques and biomarkers used to screen patients for the disease and to follow up their response to therapy. The importance of accurate assessment of right ventricular function in following up the clinical course and response to therapy is more fully appreciated. As new therapies are developed for pulmonary arterial hypertension, screening, prompt diagnosis, and accurate assessment of disease severity become increasingly important. A clear definition of pulmonary hypertension and the development of a rational approach to diagnostic assessment and follow-up using both conventional and new tools will be essential to deriving maximal benefit from our expanding therapeutic armamentarium. (J Am Coll Cardiol 2009;54:S55-66) (C) 2009 by the American College of Cardiology Foundation