A brief measure for assessing generalized anxiety disorder -: The GAD-7

A brief measure for assessing generalized anxiety disorder -: The GAD-7
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DOI:
10.1001/archinte.166.10.1092
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发表时间:
2006-05-22
影响因子:
--
通讯作者:
Loewe, Bernd
Loewe, Bernd
中科院分区:
其他
文献类型:
--
作者:
Spitzer, Robert L.;Kroenke, Kurt;Loewe, Bernd

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背景:广泛性焦虑症(GAD)是最常见的精神障碍之一;然而,目前还没有评估广泛性焦虑症的简单临床方法。本研究的目的是制定一个简短的自我报告量表,以识别可能的广泛性焦虑症病例并评估其信度和效度。方法:2004年11月至2005年6月在美国15个初级保健诊所进行了一项标准标准研究。总共2740名成年患者完成了研究问卷,其中965名患者在1周内接受了心理健康专业人士的电话采访。对于标准和结构效度,GAD 自我报告量表诊断与心理健康专业人员的独立诊断进行了比较;功能状态测量;伤残日;结果:7 项焦虑量表 (GAD-7) 具有良好的信度以及标准、结构、因子和程序效度。确定了优化敏感性 (89%) 和特异性 (82%) 的切点。量表分数的增加与多个领域的功能障碍密切相关(所有 6 项医疗结果研究简式一般健康调查量表和残疾天数)。尽管广泛性焦虑症和抑郁症状经常同时出现,但因子分析证实它们是不同的维度。此外,广泛性焦虑症和抑郁症状对功能障碍和残疾有不同但独立的影响。自我报告版本和访谈员管理版本之间存在良好的一致性。结论:GAD-7 是临床实践和研究中筛查 GAD 并评估其严重程度的有效且高效的工具。
Background: Generalized anxiety disorder (GAD) is one of the most common mental disorders; however, there is no brief clinical measure for assessing GAD. The objective of this study was to develop a brief self-report scale to identify probable cases of GAD and evaluate its reliability and validity.Methods: A criterion-standard study was performed in 15 primary care clinics in the United States from November 2004 through June 2005. Of a total of 2740 adult patients completing a study questionnaire, 965 patients had a telephone interview with a mental health professional within 1 week. For criterion and construct validity, GAD self-report scale diagnoses were compared with independent diagnoses made by mental health professionals; functional status measures; disability days; and health care use.Results: A 7-item anxiety scale (GAD-7) had good reliability, as well as criterion, construct, factorial, and procedural validity. A cut point was identified that optimized sensitivity (89%) and specificity (82%). Increasing scores on the scale were strongly associated with multiple domains of functional impairment (all 6 Medical Outcomes Study Short- Form General Health Survey scales and disability days). Although GAD and depression symptoms frequently co-occurred, factor analysis confirmed them as distinct dimensions. Moreover, GAD and depression symptoms had differing but independent effects on functional impairment and disability. There was good agreement between self- report and interviewer-administered versions of the scale.Conclusion: The GAD-7 is a valid and efficient tool for screening for GAD and assessing its severity in clinical practice and research.