Anaphylactoid reactions to tolmetin and zomepirac.
Anaphylactoid reactions to tolmetin and zomepirac.
复制标题
对托美丁和佐美拉的过敏反应。
DOI：
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发表时间：
1983
期刊：
影响因子：
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通讯作者：
Jacobs Rl
中科院分区：
文献类型：
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作者：
Rake Gw;Jacobs Rl
：一名38岁男性对托美丁和佐美酸发生持续性类速发过敏反应。这是第一次报告涉及这些密切相关的非甾体抗炎药（NSAID）在一个单一的病人。患者既往耐受其他NSAID，并耐受分级口服阿司匹林挑战（高达625 mg），无反应。托美丁和佐美酸的水性白蛋白提取物的皮肤试验结果为阴性。这些反应似乎与先前描述的阿司匹林（NSAID）敏感性不同。医生应注意这两种制剂的治疗中断。
: A 38-year-old male sustained sequential anaphylactoid reactions to tolmetin and zomepirac. This is the first report involving these closely related non-steroidal anti-inflammatory drugs (NSAID) in a single patient. He was historically tolerant of other NSAID and tolerated a graded oral aspirin challenge (up to 625 mg) without reaction. Skin testing with aqueous albumin extracts of tolmetin and zomepirac was negative. These reactions appear to differ from previously described aspirin (NSAID) sensitivity. Physicians should beware of interrupted treatment with either of these preparations.