DIFFERENCE BETWEEN END-TIDAL AND ARTERIAL PCO2 IN EXERCISE
DIFFERENCE BETWEEN END-TIDAL AND ARTERIAL PCO2 IN EXERCISE
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DOI：
10.1152/jappl.1979.47.5.954
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发表时间：
1979-01-01
影响因子：
3.3
通讯作者：
KANE, JW
中科院分区：
文献类型：
--
作者：
JONES, NL;ROBERTSON, DG;KANE, JW
对5名健康成人在2种功率输出(25和50%最大摄氧量)和3种呼吸频率(15、30和45次/min)下，用红外光谱仪测定的呼气末二氧化碳分压(PETCO2)与运动时动脉二氧化碳分压(PaCO2)的关系进行了系统的研究。PETCO2-PaCO2在-2.5Torr~+9.1Torr之间变化，与呼吸频率呈负相关(r[相关系数]=0.475)，与潮气量(VT；r=0.791)和二氧化碳排出量(r=0.627)呈正相关。通过多元回归分析得到由PETCO_2预测PaCO_2的方程：PaCO_2=5.5+0.90PETCO_2-0.0021 VT(r=0.915)。将该方程应用于在10个受试者的两项先前研究中获得的PETCO2的测量，其中测量了PaCO2，并预测PaCO2在1.04 Torr(.+-.SD)，PaCO2在25至58Torr之间(n[数字]=56；r=0.962)。通过与快速响应呼吸质谱计的比较，系统地考察了CO2分析仪的响应特性对PETCO2测量的影响。
The relation between end-tidal CO2 tension (PETCO2) measured by IR analysis and arterial CO2 tension (PaCO2) during exercise was systematically examined in 5 healthy adults at 2 power outputs (25 and 50% .ovrhdot.VO2 max) and at 3 breathing frequencies (15, 30 and 45 breaths/min). PETCO2-PaCO2 varied between -2.5 and +9.1 Torr, was inversely related to the frequency of breathing (r [correlation coefficient] = 0.475) and directly related to tidal volume (VT; r = 0.791) and CO2 output (r = 0.627). An equation was obtained by multiple regression analysis, to predict PaCO2 from PETCO2: PaCO2 = 5.5 + 0.90 PETCO2 -0.0021 VT (r = 0.915). The equation was applied to measurements of PETCO2 obtained in 2 previous studies in 10 subjects in which PaCO2 was measured and was predicted PaCO2 to within 1.04 Torr (.+-. SD) for PaCO2 between 25 and 58 Torr (n [number] = 56; r = 0.962). The effect of the response characteristics of the CO2 analyzer on the measurement of PETCO2 was systematically examined by comparison with a fast-responding respiratory mass spectrometer.