Generic antiretroviral efficacy in AIDS-associated Kaposi's sarcoma in sub-Saharan Africa.
Generic antiretroviral efficacy in AIDS-associated Kaposi's sarcoma in sub-Saharan Africa.
复制标题
撒哈拉以南非洲地区与艾滋病相关的卡波西肉瘤的一般抗逆转录病毒疗效。
DOI：
10.1097/01.aids.0000161775.36652.85
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发表时间：
2005
期刊：
影响因子：
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通讯作者：
Coovadia,HoosenM
中科院分区：
文献类型：
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作者：
Mosam,Anisa;Cassol,Edana;Page,Taryn;Bodasing,Uvani;Cassol,Sharon;Dawood,Halima;Friedland,GeraldH;Scadden,DavidT;Aboobaker,Jamila;Jordaan,JacobusP;Lalloo,UmeshG;Esterhuizen,TonyaM;Coovadia,HoosenM
Generic antiretroviral drugs are pivotal in the implementation of WHO's ‘3 by 5’programme. However, clinical experience with generics in sub-Saharan Africa is insufficiently documented. We report on 50 patients with HIV-associated Kaposi's sarcoma treated with generic fixed-dose highly active antiretroviral therapy. At 52 weeks, 74% achieved an undetectable viral load of< 50 copies/ml, 86% achieved< 400 copies/ml, and a 3.1 log 10 decline from baseline. Side-effects were minimal. The outcomes support the use of generic antiretroviral therapy.
