An Attempt to Target Anxiety Sensitivity via Cognitive Bias Modification
An Attempt to Target Anxiety Sensitivity via Cognitive Bias Modification
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DOI：
10.1371/journal.pone.0114578
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发表时间：
2015-02-18
期刊：
影响因子：
3.7
通讯作者：
Schofield, Casey A.
中科院分区：
文献类型：
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作者：
Clerkin, Elise M.;Beard, Courtney;Schofield, Casey A.
我们本研究的目标是测试认知偏差修正计划的适应性，以降低焦虑敏感性，并评估生理线索的解释偏差、焦虑敏感性以及与内感受暴露相关的焦虑和回避之间的因果关系。患有恐慌症或有限症状发作的焦虑敏感性较高的参与者被随机分配到解释修改计划（IMP；n = 33）或对照（n = 32）条件组。在解释修改训练期间（通过单词句子关联范式），参与者阅读描述模糊的恐慌相关生理和认知症状的短句子，并接受训练以认可良性解释并拒绝与这些线索相关的威胁性解释。与对照条件相比，IMP 训练在第 2 次访视时成功增加了对良性解释的认可度，并减少了对威胁性解释的认可度。虽然自我报告的焦虑敏感性从预选到访视 1 以及从访视 1 到访视 2 有所下降，但实验条件与对照条件相比，降低幅度并不大。此外，IMP（与对照）训练的参与者并没有减少与内感受暴露相关的焦虑和回避。事实上，有一些证据表明，处于控制状态的人在训练后经历了较少的回避。讨论了无效结果的潜在解释，包括良性恐慌相关刺激的问题和控制条件的局限性。
Our goals in the present study were to test an adaptation of a Cognitive Bias Modification program to reduce anxiety sensitivity, and to evaluate the causal relationships between interpretation bias of physiological cues, anxiety sensitivity, and anxiety and avoidance associated with interoceptive exposures. Participants with elevated anxiety sensitivity who endorsed having a panic attack or limited symptom attack were randomly assigned to either an Interpretation Modification Program (IMP; n = 33) or a Control (n = 32) condition. During interpretation modification training (via the Word Sentence Association Paradigm), participants read short sentences describing ambiguous panic-relevant physiological and cognitive symptoms and were trained to endorse benign interpretations and reject threatening interpretations associated with these cues. Compared to the Control condition, IMP training successfully increased endorsements of benign interpretations and decreased endorsements of threatening interpretations at visit 2. Although self-reported anxiety sensitivity decreased from pre-selection to visit 1 and from visit 1 to visit 2, the reduction was not larger for the experimental versus control condition. Further, participants in IMP (vs. Control) training did not experience less anxiety and avoidance associated with interoceptive exposures. In fact, there was some evidence that those in the Control condition experienced less avoidance following training. Potential explanations for the null findings, including problems with the benign panic-relevant stimuli and limitations with the control condition, are discussed.