ENHANCEMENT OF VIRULENCE OF 2 ENVIRONMENTAL STRAINS OF VIBRIO-VULNIFICUS AFTER PASSAGE THROUGH MICE
ENHANCEMENT OF VIRULENCE OF 2 ENVIRONMENTAL STRAINS OF VIBRIO-VULNIFICUS AFTER PASSAGE THROUGH MICE
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DOI：
10.1016/0732-8893(90)90018-q
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发表时间：
1990-07-01
影响因子：
2.9
通讯作者：
ABEYTA, C
中科院分区：
文献类型：
--
作者：
KAYSNER, CA;WEKELL, MM;ABEYTA, C
通过小鼠传代，两株创伤弧菌对铁负荷成年小鼠的毒力增强。通过终点滴定确定的50%致死剂量值(LD50)的估计值对这两个菌株分别减少了100倍和1000倍。通过小鼠也是因为创伤弧菌不透明的菌落类型的阶段变化，其他人报告说，对小鼠的毒力比半透明的菌落类型更强。
The virulence of two environmental strains of Vibrio vulnificus to iron-loaded adult mice was enhanced by passage through mice. Estimates of 50% lethal dose values (LD50) determined by end point titration were reduced 100- and 1000-fold for the two strains. Passage through mice also selected for the opaque colony type phase variation of V. vulnificus, reported by others to be more virulent to mice than a translucent colony type.