The value of acute-phase protein measurements after curative gastric cancer surgery
The value of acute-phase protein measurements after curative gastric cancer surgery
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DOI：
10.1001/archsurg.134.1.73
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发表时间：
1999-01-01
影响因子：
--
通讯作者：
Yamazaki, Y
中科院分区：
文献类型：
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作者：
Fujita, T;Hara, A;Yamazaki, Y
目的：为了确定急性时相蛋白测量是否提供了临床有用的信息肿瘤recursion.Patients和方法：急性时相血清蛋白水平测定定期在43例胃癌根治性胃切除术。在手术后12个月，患者进行分组，根据存在或不存在的C-反应蛋白反应，并随访了至少12个月或直到death.Results：有一个显着差异（P= 0.02）的复发率与C-反应蛋白反应（3 4例患者）和那些没有这样的反应（4 39例患者）之间。此外，术后12个月最终复发患者的血清C4和α（1）-抗胰蛋白酶水平显著高于术后12个月（P
Objective: To determine whether acute-phase protein measurement provides clinically useful information about tumor recurrence.Patients and Methods: Acute-phase serum protein levels were measured at regular intervals in 43 patients who underwent curative gastrectomy for gastric cancer. At 12 months after surgery, patients were grouped according to the presence or absence of a C-reactive protein response, and were followed up for a minimum of 12 months or until death.Results: There was a significant difference (P=.02) in a recurrence rate between patients with a C-reactive protein response (3 of 4 patients) and those without such a response (4 of 39 patients). Moreover, serum levels of C4 and alpha(1)-antitrypsin 12 months after surgery in patients who eventually recurred were significantly (P