Archaeal tetraether lipids - Unique structures and applications
Archaeal tetraether lipids - Unique structures and applications
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DOI：
10.1385/abab:97:1:45
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发表时间：
2002-01-01
影响因子：
3
通讯作者：
Peeples, TL
中科院分区：
文献类型：
--
作者：
Hanford, M;Peeples, TL
由极端环境中的生物体制造的极其稳定的生物分子在开发鲁棒和稳定的工业生物催化剂方面具有巨大的科学和工程兴趣。鉴定在极端条件下赋予稳定性的分子也将对我们理解细胞存活产生深远的影响。本文综述了古生菌四醚的分离和表征以及四醚脂质应用的目标技术。古生菌四醚脂质的分离和表征导致了一些有趣的应用，改进了酯脂质技术。潜在的应用包括新型润滑剂、基因传递系统、传感器设备的单层脂质基质和蛋白质稳定。在这篇综述之后，列出了与古细菌膜脂的分离、表征和应用有关的专利摘要和其他文献。
The extremely stable biomolecules manufactured by organisms from extreme environments are of great scientific and engineering interest in the development of robust and stable industrial biocatalysts. Identification of molecules that impart stability under extremes will also have a profound impact on our understanding of cellular survival. This review discusses isolation and characterization of archaeal tetraethers as well as target technologies for tetraether lipid application. The isolation and characterization of archaeal tetraether lipids has led to some interesting applications improving on ester lipid technologies. Potential applications include novel lubricants, gene-delivery systems, monolayer lipid matrices for sensor devices, and protein stabilization. Following this review, patent abstracts and additional literature pertaining to the isolation, characterization, and application of archaeal membrane lipids are listed.