A facile electrochemical chiral sensor for tryptophan enantiomers based on multiwalled carbon nanotube/hydroxypropyl-β-cyclodextrin functionalized carboxymethyl cellulose
A facile electrochemical chiral sensor for tryptophan enantiomers based on multiwalled carbon nanotube/hydroxypropyl-β-cyclodextrin functionalized carboxymethyl cellulose
复制标题
基于多壁碳纳米管/羟丙基-β-环糊精功能化羧甲基纤维素的色氨酸对映体的简便电化学手性传感器
DOI：
10.1016/j.microc.2021.107133
复制
发表时间：
2021-12-31
影响因子：
4.8
通讯作者：
Yang, Guang
中科院分区：
文献类型：
--
作者：
Ji, Jie;Qu, Lihang;Yang, Guang
The development of facile and convenient sensors for the chiral recognition of enantiomers is of great signifi-cance for medical and life science. Herein, a sensitive electrochemical sensor for the chiral recognition of tryptophan (Trp) enantiomers was developed based on the assembly of cellulose grafted with hydroxypropyl-beta-cyclodextrins (CMC-CD), multi-walled carbon nanotubes (MWCNTs) and copper ions on the surface of a GCE. The morphologies and electrochemical behaviors of the prepared electrode (GCE/MWCNTs/CMC-CD-Cu) were characterized by differential pulse voltammetry (DPV), FT-IR, XPS, cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). The oxidation peak current ratio (I-L/I-D) of DPV could be reached at 2.2 under the optimal experimental conditions. Compared with D-Trp, the higher electrochemical signal of L-Trp was ascribed to the stronger affinity for L-type tryptophan. Additionally, the as-prepared chiral sensor was successfully utilized to analyze the amount of D-Trp in the racemic mixture.
