Thermally reversible formation of microspheres through non-covalent polymer cross-linking.
Thermally reversible formation of microspheres through non-covalent polymer cross-linking.
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DOI：
10.1021/ja034868b
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发表时间：
2003-08
影响因子：
15
通讯作者：
Raymond J. Thibault;Peter J. Hotchkiss;M. Gray;V. Rotello
中科院分区：
文献类型：
--
作者：
Raymond J. Thibault;Peter J. Hotchkiss;M. Gray;V. Rotello
双胸腺嘧啶单元被用来非共价交联一个互补的二氨基吡啶功能化的共聚物。在非竞争性溶剂中结合，通过特定的三点聚合物-交联剂氢键作用形成离散的微米级球形聚集体。这些微球的直径可以通过间隔结构来控制。交联过程是完全热可逆的，在50摄氏度时观察到完全溶解，当回到环境温度时聚集体重新形成。这一过程可以重复倍增，同时观察到较低的粒子分散性产生于退火过程。
Bis-thymine units were used to noncovalently cross-link a complementary diamidopyridine-functionalized copolymer. Upon combination in noncompetitive solvents, discrete micron-scale spherical aggregates were formed arising from specific three-point polymer-cross-linker hydrogen bonding interactions. The diameter of these microspheres could be controlled through spacer structure. The cross-linking process was fully thermally reversible, with complete dissolution observed at 50 degrees C and reformation of the aggregates upon return to ambient temperature. This process could be repeated multiply, with lower particle dispersity observed arising from the annealing process.