Autotransplantation or replantation of cryopreserved teeth: a case series and literature review
Autotransplantation or replantation of cryopreserved teeth: a case series and literature review
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冷冻保存牙的自体移植或再植：病例系列和文献综述
DOI：
10.1111/edt.12039
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发表时间：
2013
期刊：
影响因子：
2.5
通讯作者：
Saito C
中科院分区：
文献类型：
--
作者：
Yoshizawa M;Koyama T;Izumi N;Niimi K;Ono Y;Ajima H;Funayama A;Mikami T;Kobayashi T;Ono K;Takagi R;Saito C
背景本报告的目的是评估临床和影像学的结果自体移植或再植冷冻保存的牙齿。将供体牙齿在使用5%二甲基亚砜（DMSO）和6%羟乙基淀粉（HES）作为保护剂的受控速率冷冻机中缓慢冷冻。七个冷冻保存的牙齿，与存储时间从4到36个月不等，自体移植或再植在新泻大学医学和牙科医院。术后3周开始进行根管治疗，包括根管清创术，然后用氢氧化钙进行临时根管充填，并继续以2周至3个月的间隔更换氢氧化钙充填物。三个移植显示牙周再生的临床和放射学，而替代根吸收观察其余移植。从结果可以得出结论，冷冻保存的牙齿自体移植具有潜在的临床应用，但是，替代牙根吸收的风险仍然存在。
BackgroundThe aim of this report was to evaluate the outcome of autotransplantation or replantation of cryopreserved teeth clinically and radiographically. Donor teeth were slowly frozen in a controlled‐rate freezer using 5% dimethylsulfoxide (DMSO) and 6% hydroxyethyl starch (HES) as protectants. Seven cryopreserved teeth, with duration of storage ranging from 4 to 36 months, were autotransplanted or replanted at Niigata University Medical and Dental Hospital. Endodontic treatment involving root canal debridement followed by interim root canal filling with calcium hydroxide was started 3 weeks after the operation and continued with replacement of the calcium hydroxide filling at 2‐week to 3‐month intervals. Three transplants showed periodontal regeneration clinically and radiographically, whereas replacement root resorption was observed in the remaining transplants. From the results, it can be concluded that cryopreserved tooth autotransplantation has potential for clinical use; however, the risk of replacement root resorption remains.