Topographical Heterogeneity of Alzheimer's Disease Based on MR Imaging, Tau PET, and Amyloid PET
Topographical Heterogeneity of Alzheimer's Disease Based on MR Imaging, Tau PET, and Amyloid PET
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基于MR成像、Tau PET和淀粉样蛋白PET的阿尔茨海默病的局部异质性
DOI：
10.3389/fnagi.2019.00211
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发表时间：
2019-08-20
影响因子：
4.8
通讯作者：
Noh, Young
中科院分区：
文献类型：
--
作者：
Jeon, Seun;Kang, Jae Myeong;Noh, Young
Alzheimer's disease (AD) patients are known to have heterogeneous clinical presentation and pathologic patterns. We hypothesize that AD dementia can be categorized into subtypes based on multimodal imaging biomarkers such as magnetic resonance imaging (MRI), tau positron emission tomography (PET), and amyloid PET. We collected 3T MRI, F-18-THK5351 PET, and F-18-flutemetamol (FLUTE) PET data from 83 patients with AD dementia [ Clinical Dementia Rating (CDR)
