Intrinsic Fluorescence-Based Optical Fiber Sensor for Cocaine Using a Molecularly Imprinted Polymer as the Recognition Element
Intrinsic Fluorescence-Based Optical Fiber Sensor for Cocaine Using a Molecularly Imprinted Polymer as the Recognition Element
复制标题
DOI：
10.1109/jsen.2011.2158537
复制
发表时间：
2012-01-01
影响因子：
4.3
通讯作者：
Grattan, Kenneth T. V.
中科院分区：
文献类型：
--
作者：
Nguyen, T. Hien;Hardwick, Sheila A.;Grattan, Kenneth T. V.
基于含有荧光素部分作为信号基团的分子印迹聚合物（MIP），开发了一种用于检测可卡因的光纤化学传感器。荧光 MIP 形成并共价连接到光纤的远端。该传感器在乙腈水溶液混合物中对浓度范围为0-500μM的可卡因表现出荧光强度的增加，并且在一个月内具有良好的重现性。可卡因相对于其他药物的选择性也已得到证实。
A fiber-optic chemical sensor for the detection of cocaine has been developed, based on a molecularly imprinted polymer (MIP) containing a fluorescein moiety as the signalling group. The fluorescent MIP was formed and covalently attached to the distal end of an optical fiber. The sensor exhibited an increase in fluorescence intensity in response to cocaine in the concentration range of 0 - 500 mu M in aqueous acetonitrile mixtures with good reproducibility over one month. Selectivity for cocaine over others drugs has also been demonstrated.