Reversible alteration in the neuromuscular junctions of Drosophila melanogaster bearing a temperature-sensitive mutation, shibire
Reversible alteration in the neuromuscular junctions of Drosophila melanogaster bearing a temperature-sensitive mutation, shibire
复制标题
携带温度敏感突变 shibire 的黑腹果蝇神经肌肉接头的可逆改变
作者：
C. Poodry;L. Edgar
在这项研究中，我们报告了胫骨肌神经肌肉接头的超微结构与温度诱导的瘫痪的关系。果蝇神经肌肉接头的突触小泡数量减少，保持在29度或以上。在回到22摄氏度后不久，突触小泡再次大量出现。预先用河豚毒素或巴比妥酸盐处理可以保护接头免受形态上的温度变化的影响。
In this study we report a relationship between the ultrastruct of the neuromuscular junctions of tibial muscles and the temperature-induced paralysis in shibire flies. There is a decrease in the number of synaptic vesicles of neuromuscular junctions in flies which are held at or above 29 degrees. Shortly after return to 22 degrees C, the synaptic vesicles are again present in large numbers. Prior treatment with tetrodotoxin or barbiturate protects the junctions from the temperature change in morphology.