Novel biocatalysts for white biotechnology
Novel biocatalysts for white biotechnology
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DOI：
10.1002/biot.200600059
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发表时间：
2006-08-01
影响因子：
4.7
通讯作者：
Jaeger, Karl-Erich
中科院分区：
文献类型：
--
作者：
Drepper, Thomas;Eggert, Thorsten;Jaeger, Karl-Erich
怀特生物技术利用微生物和酶来制造多种化学产品。因此，对新型有用的生物催化剂的需求正在稳步快速增加。我们开发了分离新酶基因的方法，构建了新的表达系统，并通过定向进化的方法优化了现有的酶以用于生物技术应用。此外，我们还分离并表征了与制备对映体纯化合物相关的生物催化剂。
White Biotechnology uses microorganisms and enzymes to manufacture a large variety of chemical products. Therefore, the demand for new and useful biocatalysts is steadily and rapidly increasing. We have developed methods for the isolation of new enzyme genes, constructed novel expression systems, and optimized existing enzymes for biotechnological applications by methods of directed evolution. Furthermore, we have isolated and characterized biocatalysts relevant for the preparation of enantiopure compounds.