Bioactive and marker compounds from two edible dark-colored Myrciaria fruits and the synthesis of jaboticabin.
Bioactive and marker compounds from two edible dark-colored Myrciaria fruits and the synthesis of jaboticabin.
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DOI：
10.1021/jf400487g
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发表时间：
2013-04
影响因子：
6.1
通讯作者：
Shi-Biao Wu;Jing Wu;Z. Yin;Jinzhu Zhang;C. Long;E. Kennelly;Shengping Zheng
中科院分区：
文献类型：
--
作者：
Shi-Biao Wu;Jing Wu;Z. Yin;Jinzhu Zhang;C. Long;E. Kennelly;Shengping Zheng
Jaboticaba (Myrciaria cauliflora) 和 false jaboticaba (Myrciaria vexator) 果实是两种味道宜人的深色水果，原产于巴西。它们是酚类化合物的丰富来源，包括花青素、类黄酮、酚酸和单宁，以及不太为人所知的多酚，如缩酚酸。这两种水果在形态上非常相似，但它们的味道却截然不同。本研究的重点是利用 HPLC-PDA 和 LC-TOF-MS 结合主成分分析来鉴定它们之间的标记化合物。结果发现花青素-3-O-葡萄糖苷是Myrciaria果实中的主要花青素。发现飞燕草素-3-O-葡萄糖苷是假花木的标记化合物，花青素-3-O-半乳糖苷和花青素-3-O-阿拉伯糖是区分假花木的两种标记化合物。此外，首次从这两种水果中分离鉴定出两种鞣花单宁，异月见草素C和月见草素C。 Jaboticabin 是一种次要的生物活性缩酚酸，存在于两种水果中，由于其治疗慢性阻塞性肺病的潜力，因此在实验室中成功合成。
Jaboticaba (Myrciaria cauliflora) and false jaboticaba (Myrciaria vexator) fruits are two pleasant-tasting, dark-colored fruits, native to Brazil. They are rich sources of phenolic compounds, including anthocyanins, flavonoids, phenolic acids, and tannins, as well as less well known polyphenols such as depsides. These two fruits are very similar in morphology, but their taste profiles differ markedly. This study was focused on identifying the marker compounds between them using HPLC-PDA and LC-TOF-MS, combined with principal component analysis. As a result, cyanidin-3-O-glucoside was found as the major anthocyanin in Myrciaria fruits. Delphinidin-3-O-glucoside was found to be the marker compound for jaboticaba, while cyanidin-3-O-galactoside and cyanidin-3-O-arabinose were two marker compounds distinguishing false jaboticaba. In addition, two ellagitannins, iso-oenothein C and oenothein C, were isolated and identified from both of these fruits for the first time. Jaboticabin, a minor bioactive depside, occurred in both fruits and, because of its potential to treat chronic obstructive pulmonary disease, was successfully synthesized in the laboratory.