Effects of intravenous catheter on sleep in healthy men and in depressed patients.
Effects of intravenous catheter on sleep in healthy men and in depressed patients.
复制标题
静脉导管对健康男性和抑郁症患者睡眠的影响。
作者：
M. Kerkhofs;P. Linkowski;J. Mendlewicz
研究人员在 8 名男性健康对照者和 12 名抑郁症患者中研究了静脉导管和频繁的夜间采血对睡眠脑电图 (EEG) 变量的影响，这些患者在相同的实验条件下进行了研究。经过一晚的习惯后，在睡眠实验室连续记录 4 晚的睡眠情况。第四晚前一天中午左右插入导管，每 15 分钟取样一次，持续 25 小时。睡眠脑电图变量的夜间比较没有显示对照组受试者的睡眠连续性发生显着变化，除了在使用导管的夜间夜间觉醒增加的微弱趋势之外。抑郁症患者第四晚的入睡潜伏期延长。两组的快速眼动 (REM) 睡眠百分比没有检测到显着变化。然而，在 4 个晚上观察到对照受试者的第 3 阶段逐渐增加。这些结果表明，可以通过导管进行静脉血液采样，而不会导致睡眠长度和结构的显着破坏。
The effects of intravenous catheter and nocturnal blood samplings at frequent intervals on sleep electroencephalogram (EEG) variables were investigated in 8 male healthy controls and 12 depressed patients, who were studied in the same experimental conditions. After one night of habituation, sleep was recorded during 4 consecutive nights in the sleep laboratory. A catheter was inserted around noon the day before the fourth night, and blood was sampled every 15 min for 25 h. The night-to-night comparison of sleep EEG variables did not show significant sleep continuity modifications in the control subjects, other than a weak trend toward an increase in nocturnal awakenings during the night with the catheter. A lengthening of sleep onset latency during the fourth night was found in the depressed patients. No significant changes were detected in percentage of rapid eye movement (REM) sleep in the two groups. However, a gradual increase in Stage 3 was observed across the 4 nights in the control subjects. These results indicate that intravenous blood sampling via a catheter can be performed without inducing significant disruption of sleep length and structure.
减少抑郁症中的皮质醇潜伏期。
影响因子：
--
作者：
Jarrett,DB;Coble,PA;Kupfer,DJ
通讯作者：
Kupfer,DJ
夜间静脉插管对睡眠脑电图测量的影响。
影响因子：
10.6
作者：
Jarrett,DB;Greenhouse,JB;Thompson,SB;McEachran,A;Coble,P;Kupfer,DJ
通讯作者：
Kupfer,DJ