DIVIDED ATTENTION PERFORMANCE IN CANNABIS USERS AND NON-USERS FOLLOWING ALCOHOL AND CANNABIS SEPARATELY AND IN COMBINATION

DIVIDED ATTENTION PERFORMANCE IN CANNABIS USERS AND NON-USERS FOLLOWING ALCOHOL AND CANNABIS SEPARATELY AND IN COMBINATION
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DOI:
10.1007/bf00445566
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发表时间:
1989-01-01
期刊:
影响因子:
3.4
通讯作者:
MACAVOY, MG
MACAVOY, MG
中科院分区:
医学3区
文献类型:
--
作者:
MARKS, DF;MACAVOY, MG

文献摘要

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Δ的影响9-四氢大麻酚(Δ9-THC)和酒精,单独和组合,对分散注意力的表现进行了调查,大麻用户和非用户谁是匹配的酒精使用。大麻和酒精都在中枢和外周信号检测中产生了递减。药物和酒精对外周信号的影响更大。大麻使用者在大麻和/或酒精中毒时,外周信号检测受损程度低于非使用者。这些研究结果表明,在常规大麻使用者和/或补偿中毒影响的能力中,耐受性和交叉耐受性的发展。
The effect of .DELTA. 9-tetrahydrocannabinol (.DELTA. 9-THC) and alcohol, singly and in combination, on divided attention performance was investigated in cannabis users and non-users who were matched for alcohol use. Both cannabis and alcohol produced decrements in central and peripheral signal detections. Drug and alcohol effects were greater for signal presentations in the periphery. Cannabis users were less impaired in peripheral signal detection than non-users while intoxicated by cannabis and/or alcohol. These findings suggest the development of tolerance and cross-tolerance in regular cannabis users and/or the ability to compensate for intoxication effects.