A benchmark test for a quantitative assessment of simple neuron models

A benchmark test for a quantitative assessment of simple neuron models
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DOI:
10.1016/j.jneumeth.2007.11.006
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发表时间:
2008-04-30
影响因子:
3
通讯作者:
Gerstner, Wulfram
Gerstner, Wulfram
中科院分区:
医学4区
文献类型:
--
作者:
Jolivet, Renaud;Kobayashi, Ryota;Gerstner, Wulfram

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最近已经提出了几种方法和算法,允许从细胞内或细胞外记录的简单神经元模型的系统评价。以这种方式建立的模型生成良好的定量预测下的时间结构化的电流注入神经元的未来活动。然而,很难比较各种模型和算法的优点,因为每个模型都是为不同的数据集设计的。在这里,我们报告的第一次尝试建立一个基准测试,允许系统的比较方法和性能预测大鼠皮质锥体神经元的活动。我们提出了早期提交的基准测试,并讨论了未来的测试和简单的神经元模型的设计的影响。(c)2007 Elsevier B.V.保留所有权利。
Several methods and algorithms have recently been proposed that allow for the systematic evaluation of simple neuron models from intracellular or extracellular recordings. Models built in this way generate good quantitative predictions of the future activity of neurons under temporally structured current injection. It is, however, difficult to compare the advantages of various models and algorithms since each model is designed for a different set of data. Here, we report about one of the first attempts to establish a benchmark test that permits a systematic comparison of methods and performances in predicting the activity of rat cortical pyramidal neurons. We present early submissions to the benchmark test and discuss implications for the design of future tests and simple neurons models. (c) 2007 Elsevier B.V. All rights reserved.