In vitro study of the effects of fluoride-releasing dental materials on remineralization in an enamel erosion model

In vitro study of the effects of fluoride-releasing dental materials on remineralization in an enamel erosion model
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释放氟化物的牙科材料对牙釉质侵蚀模型中再矿化影响的体外研究

DOI:
10.1016/j.jdent.2011.12.016
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发表时间:
2012-03-01
影响因子:
4.4
通讯作者:
Xuan, Kun
Xuan, Kun
中科院分区:
医学2区
文献类型:
--
作者:
Zhou, San Ling;Zhou, Jun;Xuan, Kun

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目的:比较5种再矿化方案对牛牙釉质再矿化后的荧光强度、表面显微硬度、粗糙度和显微结构的影响。方法:将100颗牛切牙分为5组:(1)ClinPro(TM)XT清漆(CV);(2)F-清漆(FV);(3)Tooth Mousse(TM);(4)Fuji III LC(C)光固化玻璃离子窝沟封闭剂(FJ);(5)基底胶(C)玻璃聚烯醇酸盐胶(BC)。用定量光诱导荧光、显微硬度、表面三维形貌和扫描电子显微镜(SEM)四种不同的方法对其进行检测。结果:再矿化后,CV、BC和FJ组的荧光强度损失明显减少(p<0.05)。再矿化6周后,BC组的显微硬度值显著高于其他组(p<0.05)。再矿化6周后,CV组的表面粗糙度明显低于其他两组(p<0.05)。在显微结构方面,FV组在再矿化后的牛牙釉质中沉积了许多圆形颗粒。结论:玻璃离子水门汀(GIC)比氟化钠(NaF)更能促进人工牙釉质病变的再矿化。树脂修饰的GIC材料(如CV和FJ)有可能更好地控制和持续释放再矿化剂。TM的作用有待进一步研究。皇冠版权所有(C)2011由爱思唯尔有限公司出版。保留所有权利。
Objectives: This study was conducted to compare the remineralization effects of five regimens on the loss of fluorescence intensity, surface microhardness, roughness and microstructure of bovine enamel after remineralization. We hope that these results can provide some basis for the clinical application of these materials.Methods: One hundred bovine incisors were prepared and divided into the following five groups, which were treated with distinct dental materials: (1) Clinpro (TM) XT varnish (CV), (2) F-varnish (FV), (3) Tooth Mousse (TM), (4) Fuji III LC (c) light-cured glass ionomer pit and fissure sealant (FJ) and (5) Base Cement (c) glass polyalkenoate cement (BC). Subsequently, they were detected using four different methods: quantitative light-induced fluorescence, microhardness, surface 3D topography and scanning electron microscopy (SEM).Results: The loss of fluorescence intensity of CV, BC and FJ groups showed significant decreases after remineralization (p < 0.05). The microhardness values of the BC group were significantly higher than those of the other groups (p < 0.05) after 6 weeks of remineralization. The CV group's surface roughness was significantly lower than those of the other groups after 6 weeks of remineralization (p < 0.05). Regarding microstructure values, the FV group showed many round particles deposited in the bovine enamel after remineralization. However, the other four groups mainly showed needle-like crystals.Conclusions: Glass ionomer cement (GIC)-based dental materials can promote more remineralization of the artificial enamel lesions than can NaF-based dental materials. Resin-modified GIC materials (e.g., CV and FJ) have the potential for more controlled and sustained release of remineralized agents. The effect of TM requires further study. Crown Copyright (C) 2011 Published by Elsevier Ltd. All rights reserved.